ABT405

Anti-KIF5 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Kinesin heavy chain isoform 5A, Kinesin heavy chain neuron-specific 1, Neuronal kinesin heavy chain, NKHC, KIF5A
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 기술: immunocytochemistry: suitable; immunofluorescence: suitable; western blot: suitable
• UniProt 수납 번호: Q12840
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... KIF5A(3798)

설명

일반 설명

Kinesin heavy chain isoform 5A, also known as Kinesin heavy chain neuron-specific 1 or Neuronal kinesin heavy chain (NKHC), and encoded by the gene name KIF5A or NKHC1, are members of the kinesin superfamily of proteins (KIFs). These proteins are microtubuledependent motors that slide along microtubules and transport cellular organelles and mRNA to different parts of the cell. In neurons, KIF5 performs this role in an anterograde fashion from the neuronal cell body to axonal or dendritic terminals. KIF5 was initially differentiated from the ubiquitously expressed kinesin as being highly enriched in subsets of neurons and selectively concentrated in the cell body. KIF5 has at least three known isoforms; KIF5A (117 kDa), KIF5B (39 kDa), and KIF5C (39 kDa). Mutations in one of the isoforms of KIF5 (KIF5A) is thought to be involved in hereditary spastic paraplegias

특이성

This antibody recognizes all isoforms of KIF5.

면역원

Epitope: C-terminus

KLH-conjugated synthetic peptide corresponding to the C-terminus of human KIF5.

애플리케이션

Anti-KIF5 Antibody is an antibody against KIF5 for use in western blotting, ICC & immunofluorescence.

Immunocytochemistry Analysis: 5 μg/mL from a representative lot detected KIF5 in K562 cells.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected KIF5 in K562 cells.

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

품질

Evaluated by Western Blotting in K562 cell lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected KIF5 in K562 cell lysate.

표적 설명

~116 kDa observed. Uncharacterized bands may be observed in some lysate(s).

물리적 형태

Affinity

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable