ABN483

Anti-RTP801 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): DNA damage-inducible transcript 4 protein, HIF-1 responsive protein RTP801, Protein regulated in development and DNA damage response 1, REDD-1, RTP801
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: mouse, human
• 기술: immunohistochemistry: suitable; western blot: suitable
• UniProt 수납 번호: Q9NX09
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... DDIT4(54541)

설명

일반 설명

HIF-1 responsive protein RTP801, also known as DNA damage-inducible transcript 4 protein, is a member of the DDIT4 family regulating cell growth, proliferation and survival via inhibition of the activity of the mammalian target of rapamycin complex 1 (mTORC1). In response to energy stress, RTP801 inhibits mTOR function, resulting in dephosphorylation of downstream targets such as ribosomal protein S6 kinase 1 and 4EBP1 and decreasing cell growth. RTP801 is widely expressed with lowest levels in brain, skeletal muscle, and intestine.

면역원

KLH-conjugated linear peptide corresponding to human RTP801.

애플리케이션

Detect HIF-1 responsive protein RTP801 using this rabbit polyclonal antibody, Anti-RTP801 Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected RTP801 in mouse kidney tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

품질

Evaluated by Western Blotting in human kidney tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected RTP801 in 15 µg of human kidney tissue lysate.

표적 설명

~25 kDa observed. Uncharacterized bands may appear in some lysates.

물리적 형태

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Human kidney tissue lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable