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Merck
모든 사진(3)

주요 문서

ABF207

Sigma-Aldrich

Anti-TIRP Antibody

from rabbit, purified by affinity chromatography

동의어(들):

TIR domain-containing adapter molecule 2, TICAM-2, Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule, Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

rat, human, mouse

기술

immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... TICAM2(353376)

일반 설명

Toll/interleukin-1 receptor domain-containing protein (TIRP), also known as TIR domain-containing adapter molecule 2 (TICAM2), also known as Putative NF-kappa-B-activating protein 502, TRIF-related adapter molecule (TRAM), and Toll-like receptor adaptor protein 3 (TIRAP3), is an adaptor protein containing one TIR domain, and is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) serving as an important link between the innate and adaptive immune responses. TIRP is expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas.

특이성

This antibody recognizes the C-terminus of TIRP.

면역원

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of human TIRP.

애플리케이션

Detect Toll/interleukin-1 receptor domain-containing protein using this rabbit polyclonal antibody, Anti-TIRP Antibody validated for use in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected TIRP in mouse kidney tissue.

Immunofluorescence Analysis: 20 µg/mL from a representative lot detected TIRP in mouse kidney cells.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology

품질

Evaluated by Western Blotting in human, mouse, and rat kidney tissue lysates.

Western Blotting Analysis: 1 µg/mL of this antibody detected TIRP in human, mouse, and rat kidney tissue lysates.

표적 설명

~26 kDa observed. Uncharacterized bands may appear in some lysates.

물리적 형태

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Human, mouse, and rat kidney tissue lysates

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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