ABE601

Anti-CPEB1 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Cytoplasmic polyadenylation element-binding protein 1, CPE-BP1, CPE-binding protein 1, h-CEBP, hCPEB-1
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: rat
• 종 반응성(상동성에 의해 예측): human (immunogen homology)
• 기술: western blot: suitable
• UniProt 수납 번호: Q9BZB8
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CPEB1(64506)

설명

일반 설명

Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1, CPEB1) is an RNA binding protein that contains an RNA-recognition motif and a zinc finger-containing region and is found in a wide range of vertebrates and invertebrates. CPEB1 forms the nucleus of a complex of factors that regulate poly(A) elongation and promotes polyadenylation-induced translation. CPEB1 mediates many diverse biological processes such as germ cell development, cell division and senescence, and synaptic plasticity. Recently, it was discovered that CPEB1 is involved in beta-catenin mRNA translation and cell migration in astrocytes as well as regulating hypoxia-inducible factor (HIF)-1 expression, demonstrating the wide range of processes in which CPEB1 plays a role. At least four isoforms of CPEB1 are known to exist.

특이성

This antibody recognizes the N-terminus of CPEB1.

면역원

Epitope: N-terminus

KLH-conjugated linear peptide corresponding to the N-terminus of human CPEB1.

애플리케이션

Detect Cytoplasmic polyadenylation element-binding protein 1 using this rabbit polyclonal antibody, Anti-CPEB1 Antibody validated for use in western blotting.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
RNA Metabolism & Binding Proteins

품질

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected CPEB1 in 15 µg of rat brain tissue lysate.

표적 설명

~65 kDa observed. Uniprot describes 2 isoforms at ~54 kDa, one isoform at ~62 kDa, and one isoform at ~63 kDa Uncharacterized bands may appear in some lysates.

물리적 형태

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Rat brain tissue lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable