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Merck
모든 사진(1)

주요 문서

AB5372

Sigma-Aldrich

Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB

serum, Chemicon®

동의어(들):

BDNF/NT-3 Growth Factors Receptor, Tyrosine Kinase Receptor B

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

rat, human

제조업체/상표

Chemicon®

기술

immunohistochemistry: suitable
western blot: suitable

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... NTRK2(4915)

특이성

TrkB. The sequence used for the immunogen was chosen to avoid cross reactivity with trkA or trkC.

면역원

A synthetic peptide from rat trkB
Epitope: a.a. 54-67 rtrkB

애플리케이션

Anti-Trk B Antibody, pain, a.a. 54-67 rTrkB detects level of Trk B & has been published & validated for use in IH & WB.
Immunohistochemistry: 1:2,000-1:3,000. The antibody reacts well with tissue from the rat spinal cord.
Immunoblotting: 1:1,000-1:1,500 on rat membrane preparations. The antibody should be
evaluated for use in Western blot by the end user. Its utility will be dependant on the level of
the protein expressed in the tissues or cells being tested.
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

물리적 형태

Rabbit serum. Lyophilized. Contains no preservative. Reconstitute with 50 μL of sterile distilled water. Centrifuge if necessary to remove any residue.

저장 및 안정성

Maintain lyophilized material at -20°C to -70°C for up to 6 months after date of receipt. After reconstitution maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Zitao Zhang et al.
Molecular medicine reports, 15(3), 1362-1367 (2017-01-19)
Brain‑derived neurotrophic factor (BDNF), a member of the neurotropic family, is expressed in osteoblast‑like cells of a fracture callus, however, its role in fracture healing remains to be fully elucidated. Osteoblasts isolated from Sprague Dawley rats were stimulated by BDNF
Laurens W J Bosman et al.
Brain cell biology, 35(1), 87-101 (2007-10-18)
The receptor tyrosine kinase TrkB and its ligands, brain-derived neurotrophic factor (BDNF) and neurotrophin-4/5 (NT-4/5), are critically important for growth, survival and activity-dependent synaptic strengthening in the central nervous system. These TrkB-mediated actions occur in a highly cell-type specific manner.
Rita Machaalani et al.
Neurotoxicology, 74, 40-46 (2019-05-24)
Cigarette smoke exposure during pregnancy into infancy affects brain growth and development in both short and long term (into adulthood). Using a mouse model of pre- into post- natal cigarette smoke exposure (SE), we aimed to determine the effects on
Ji Min Yu et al.
Methods in molecular biology (Clifton, N.J.), 702, 219-231 (2010-11-18)
While adult stem cells can be induced to transdifferentiate into multiple lineages of cells or tissues, their plasticity and utility for human therapy remains controversial. In this chapter, we describe methods for the transdifferentiation of human adipose tissue-derived stem cells
Amy A Robinson et al.
GeroScience, 40(1), 31-47 (2018-01-23)
Mammalian aging is associated with decline in cognitive functions. Studies searching for a cause of cognitive aging initially focused on neuronal loss but quantitative investigations of rat, monkey, and human brain using stereology demonstrated that in normal aging, unlike in

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