생물학적 소스
rabbit
Quality Level
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
mouse
종 반응성(상동성에 의해 예측)
rat (100% immunogen homology), human (100% immunogen homology)
제조업체/상표
Chemicon®
기술
western blot: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... RASD1(51655)
일반 설명
Dexras1 is a member of the superfamily of RAS-g-proteins and directly binds to Gialpha heterotrimeric G-proteins where it appears to promote guanine nucleotide exchange on Gialpha. Dexras1 is implicated in NMDA receptor signaling through nitric oxide synthase.
특이성
Dexras1 (Activator of G-Protein Signaling 1, AGS1). By Western blot the antibody recognizes a band at ~33 kDa on mouse brain extract. The antibody has also been used to detect Dexras1 in brown adipocyte lysate.
Other species have not been tested
면역원
Synthetic peptide.
애플리케이션
Research Category
Neuroscience
Neuroscience
Research Sub Category
Signaling Neuroscience
Signaling Neuroscience
This Anti-Dexras1 Antibody is validated for use in WB for the detection of Dexras1.
Western blot: 1:1,000 on mouse brain extract.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
물리적 형태
ImmunoAffinity Purified
Liquid in PBS. Contains no preservative
저장 및 안정성
6 months at -70°C from date of shipment
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Marek Lenarczyk et al.
Journal of molecular histology, 46(2), 123-136 (2014-12-24)
Activators of G-protein Signaling (AGS) are a family of accessory proteins that were discovered as modulators of heterotrimeric G-protein subunits. The primary aim of the present study was to localize Group I and II AGS proteins and determine the renal
Sudhir G Tattikota et al.
Molecular & cellular proteomics : MCP, 12(5), 1214-1225 (2013-01-30)
Argonaute2 (Ago2) is an established component of the microRNA-induced silencing complex. Similar to miR-375 loss-of-function studies, inhibition of Ago2 in the pancreatic β-cell resulted in enhanced insulin release underlining the relationship between these two genes. Moreover, as the most abundant
Yu Zhang et al.
Aging cell, 17(3), e12754-e12754 (2018-03-27)
In neurons, increased protein-protein interactions between neuronal nitric oxide synthase (nNOS) and its carboxy-terminal PDZ ligand (CAPON) contribute to excitotoxicity and abnormal dendritic spine development, both of which are involved in the development of Alzheimer's disease. In models of Alzheimer's
Li-Juan Zhu et al.
Journal of neurochemistry, 146(5), 598-612 (2018-06-03)
Anxiety disorders are associated with a high social burden worldwide. Recently, increasing evidence suggests that nuclear factor kappa B (NF-κB) has significant implications for psychiatric diseases, including anxiety and depressive disorders. However, the molecular mechanisms underlying the role of NF-κB
Sudhir G Tattikota et al.
Cell metabolism, 19(1), 122-134 (2013-12-24)
Pancreatic β cells adapt to compensate for increased metabolic demand during insulin resistance. Although the microRNA pathway has an essential role in β cell proliferation, the extent of its contribution is unclear. Here, we report that miR-184 is silenced in
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