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Merck
모든 사진(1)

문서

AB1528SP

Sigma-Aldrich

Anti-Nerve Growth Factor-β Antibody

Chemicon®, from sheep

동의어(들):

NGFbeta

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

sheep

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

chicken, human, rat, mouse

반응하면 안 됨

bovine

제조업체/상표

Chemicon®

기술

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... NGF(4803)

특이성

Nerve growth factor-beta (NGF). By one site ELISA, less than 1% cross-reactivity against recombinant human BDNF or neurotrophin 4. Approximately 2% cross-reactivity against neurotrophin 3.

면역원

Mouse nerve growth factor-beta purified from salivary glands. Antigen purity greater than 95% by PAGE.

애플리케이션

Anti-Nerve Growth Factor-β Antibody is an antibody against Nerve Growth Factor-β for use in ELISA, WB, IH.
Immunohistochemistry: 1-10 μg/mL (see suggested protocol).

Immunoblotting: 1-10 μg/mL

ELISA: 1-10 μg/mL

Inhibition of biological activity in vitro: 1-10 μg/mL
BIOLOGICAL ACTIVITY: Neutralizes NGF, but not other neurotrophins.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

결합

Replaces: 04-1119

물리적 형태

Format: Purified
Protein G purified immunoglobulin. Lyophilized from PBS, no preservatives. Reconstitute with 500 μL of sterile distilled water (1 mg/mL).

저장 및 안정성

Maintain at -20 to -70°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles. Glycerol (1:1) can be added for additional stability.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

The role of mesopontine NGF in sleep and wakefulness.
Ramos, OV; Torterolo, P; Lim, V; Chase, MH; Sampogna, S; Yamuy, J
Brain Research null
Sravya Kurapati et al.
Journal of virology, 91(17) (2017-06-24)
Mechanisms of neuronal infection by varicella-zoster virus (VZV) have been challenging to study due to the relatively strict human tropism of the virus and the paucity of tractable experimental models. Cellular mitogen-activated protein kinases (MAPKs) have been shown to play
Martin Larhammar et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(46), 11074-11084 (2017-10-11)
The c-Jun-N-terminal kinase (JNK) signaling pathway regulates nervous system development, axon regeneration, and neuronal degeneration after acute injury or in chronic neurodegenerative disease. Dual leucine zipper kinase (DLK) is required for stress-induced JNK signaling in neurons, yet the factors that
Tomohiko Sadaoka et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(17), E2403-E2412 (2016-04-15)
Varicella-zoster virus (VZV) establishes latency in human sensory and cranial nerve ganglia during primary infection (varicella), and the virus can reactivate and cause zoster after primary infection. The mechanism of how the virus establishes and maintains latency and how it
Ming-Shian Tsai et al.
Experimental & molecular medicine, 50(1), e426-e426 (2018-01-13)
This study investigated the regulatory role of nerve growth factor (NGF) in sirtuin 1 (SIRT1) expression in cholestatic livers. We evaluated the expression of NGF and its cognate receptors in human livers with hepatolithiasis and the effects of NGF therapy

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