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문서

AB1094

Sigma-Aldrich

Anti-Myosin X Antibody

serum, from rabbit

동의어(들):

Unconventionnal myosin-X, Unconventional myosin-10

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

serum

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

mouse, rat, human

기술

western blot: suitable

GenBank 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... MYO10(4651)

일반 설명

Myosins are a superfamily of molecular motor proteins found in eukaryotic cells. Motor proteins are involved in muscular contraction, cytokinesis, short-range membrane/vesicle transport and a host of other cellular processes. The myosins are responsible for actin-based motility by using the energy of ATP hydrolysis to generate force and movement along actin filaments. There are many isoforms of myosin of which some have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. Myosin X belongs to a group of myosin isoforms known as unconventional myosins that participate in cellular processes ranging from membrane trafficking to signaling and cell motility. Myosin X is concentrated at the tips of filopodia and Myosin X rich regions travel forward and backward along filopods, (Berg, 2002). It also appears that Myosin X functions in actual filopodia formation, (Bohil, 2006).

특이성

Cat. No. AB1094 recognizes human Myosin X.
Predicted to cross react with mouse and rat based on 100% sequence homology. Reactivity with other species has not been tested.

면역원

Epitope: a.a. 936-953
KLH-conjugated synthetic peptide to amino acids 936-953 of human Myosin X.

애플리케이션

Detect Myosin X using this Anti-Myosin X Antibody validated for use in WB.

품질

Evaluated on a representative lot by Western blot on human head/neck lysate using Anti-Myosin X.

표적 설명

~ 108 kDa

저장 및 안정성

Maintain at -20°C for up to 1 year from date of receipt.
Upon arrival, aliquot into usable quantities to avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

분석 메모

Control
Human head/neck lysate.

법적 정보

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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