8.51021

N₃-(PEG)₇-COOH (33 atoms)

Novabiochem^®

• 동의어(들): N₃-(PEG)₇-COOH (33 atoms), O-(2-Azidoethyl)-O′-(N-diglycolyl-2-aminoethyl)-heptaethyleneglycol
• 실험식(Hill 표기법): C₂₂H₄₂N₄O₁₂
• CAS Number: 846549-37-9
• Molecular Weight: 554.59
• MDL number: MFCD10001327
• UNSPSC 코드: 12352106
• NACRES: NA.22

속성

• Quality Level: 400
• 제품 라인: Novabiochem^®
• 분석: ≥97.0% (HPLC)
• 양식: oil
• 반응 적합성: reaction type: click chemistry
• 제조업체/상표: Novabiochem^®
• 응용 분야: peptide synthesis
• 저장 온도: 2-8°C
• SMILES string: [N+](=[N-])=NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)COCC(=O)O
• InChI: 1S/C22H42N4O12/c23-26-25-2-4-31-6-8-33-10-12-35-14-16-37-18-17-36-15-13-34-11-9-32-7-5-30-3-1-24-21(27)19-38-20-22(28)29/h1-20H2,(H,24,27)(H,28,29)
• InChI key: WWDNBBVPYDZICO-UHFFFAOYSA-N

설명

일반 설명

This building block is prepared from highly purified PEG to ensure homogeneous products free from contaminating PEG oligomers. In this derivative the azido group acts as an orthogonally masked amine; it is stable to both TFA and piperidine but is easily converted to an amine by treatment with phosphines or thiols. For a similar spacer, see reference ^[1]. This material is now only available as an oil.

Associated Protocols and Technical Articles
Guide to Selection of Orthogonally-Protected Building Blocks for Fmoc SPPS

Literature references
^[1] J. Mack, et al. (1999) J. Peptide Sci., 6, 135.

결합

Replaces: 01-63-0103

분석 메모

Color (visual): slight yellow to yellow
Appearance of substance (visual): oil
Assay (HPLC, area%): ≥ 97.0 % (a/a)

법적 정보

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315 - H319 - H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable