616430

TGF-α, Human, Recombinant, E. coli

• 동의어(들): TGF-α, Human, Recombinant, E. coli, Transforming Growth Factor-α
• CAS Number: 105186-99-0
• MDL number: MFCD00082077
• UNSPSC 코드: 12352202

속성

• 분석: ≥97% (SDS-PAGE)
• Quality Level: 100
• 형태: lyophilized
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 불순물: ≤100 pg/μg Endotoxin (pg/μg TGF-α)
• 배송 상태: dry ice
• 저장 온도: −70°C

설명

일반 설명

Recombinant, human transforming growth factor-α expressed in E. coli. Plays an important role in cell-cell adhesion and cell growth and differentiation. Reported to play a role in the development of hormonal insensitivity in estrogen-receptor-positive breast cancers.

생화학적/생리학적 작용

ED₅₀= 0.1-0.4 ng/ml as measured by the ability to stimulate ³H-thymidine incorporation in the mouse fibroblast cell line Balb/3T3

경고

Toxicity: Standard Handling (A)

물리적 형태

Lyophilized from 30% acetonitrile, 0.1% TFA.

재구성

Following reconstitution, aliquot and freeze (-70°C) for long-term storage or refrigerate (4°C) for short-term storage. Avoid freeze/thaw cycles of solutions. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -70°C.

Reconstitute to a concentration of ≥10 µg/ml with sterile 10 mM acetic acid containing ≥0.1% HSA or BSA.

기타 정보

Nicholson, R.I., et al. 1994. Cancer Res. 54, 1684.
Anklesaria, P., et al. 1990. Proc. Natl. Acad. Sci. USA87, 3289.
Massague, J. 1990. J. Biol. Chem.265, 21393.
Watanabe, S., et al. 1987. Proc. Natl. Acad. Sci. USA84, 1258.
Schreiber, A.B., et al. 1986. Science232, 1250.
Tam, J.P. 1985. Science229, 673.
Derynck, R., et al. 1984. Cell38, 327.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany