552095

R-Spondin 4, Mouse, Recombinant

• 동의어(들): Cristin 4
• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 분석: ≥95% (SDS-PAGE)
• Quality Level: 100
• 형태: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze
• 불순물: <1.0 EU/μg protein Endotoxin
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

Recombinant, mouse R-Spondin 4 consisting of amino acids 19-228 and expressed in Chinese Hamster Ovary cells. Able to induce activation of β-catenin response in a Luciferase assay using HEK293T human embryonic kidney cells. R-spondin 4 is useful as a positive modulator of Wnt/β signaling.

생화학적/생리학적 작용

ED₅₀ = 5-20 ng/ml in the presence of 10 ng/ml rmWnt-3a, as measured by induction of activation of β-catenin response in a Topflash Luciferase assay using HEK293T human embryonic kidney cells.

경고

Toxicity: Standard Handling (A)

물리적 형태

Lyophilized from 0.2 µm sterile-filtered PBS, NaCl, EDTA, BSA.

재구성

Reconstitute to 200 µg/ml in PBS.

기타 정보

Hendrickx, M. and L. Leyns. 2008. Develop. Growth Differ.50, 229.
Ishii, Y., et al. 2008. J. Invest. Dermatol.128, 867.
Kim, K.A., et al. 2008. Mol. Biol. Cell19, 2588.
Binnerts, M.E., et al. 2007. Proc. Natl. Acad. Sci. USA104 14700.
Nam, J.S., et al. 2007. Gene Expr. Patterns7, 306.
Pemberton, T.J., et al. 2007. Dev. Dyn.236, 2245.
Bergmann, C., et al. 2006. Am. J. Hum. Genet.79, 1105.
Blaydon, D.C., et al. 2006. Nat. Genet.38, 1245.
Nam, J.S., et al. 2006. J. Biol. Chem.281, 13247.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable