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Merck
모든 사진(1)

문서

540223

Sigma-Aldrich

Purmorphamine

≥98% (HPLC), liquid, Hedgehog signaling activator, Calbiochem

동의어(들):

InSolution Purmorphamine

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About This Item

UNSPSC 코드:
12352116
NACRES:
NA.77

product name

Purmorphamine, InSolution, ≥98%, 50 mM in DMSO, induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells

Quality Level

분석

≥98% (HPLC)

형태

liquid

제조업체/상표

Calbiochem®

저장 조건

OK to freeze
desiccated (hygroscopic)
protect from light

저장 온도

−20°C

일반 설명

A cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.

애플리케이션

InSolution Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.

포장

Packaged under inert gas

경고

Toxicity: Irritant (B)

물리적 형태

A 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.

재구성

Following initial thaw, aliquot and freeze (-20°C).

기타 정보

Wu, X., et al. 2004. Chem. Biol.11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Health hazard

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Muta. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

188.6 °F - closed cup

Flash Point (°C)

87 °C - closed cup


시험 성적서(COA)

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