5.05313

Hexamethonium Bromide

• 동의어(들): Hexamethonium Bromide, Hexane-1,6-bis(trimethylammonium bromide), Nicotinic Acetylcholine Receptors (nAChRs) Antagonist, Hexamethonium Bromide
• 실험식(Hill 표기법): C₁₂H₃₀Br₂N₂
• CAS Number: 55-97-0
• Molecular Weight: 362.19
• MDL number: MFCD00011787
• UNSPSC 코드: 12352200

속성

• 분석: ≥98% (TLC)
• Quality Level: 100
• 양식: powder
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: white
• solubility: H₂O: 100 mg/mL
• 저장 온도: 10-30°C
• InChI: 1S/C12H30N2.2BrH/c1-13(2,3)11-9-7-8-10-12-14(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2
• InChI key: FAPSXSAPXXJTOU-UHFFFAOYSA-L

설명

일반 설명

A potent antagonist of nicotinic acetylcholine receptors (nAChRs) at pre-ganglionic sites in both the sympathetic and parasympathetic nervous systems. Often used for studying the roles of nicotinic receptors in regulating cardiovascular system.

생화학적/생리학적 작용

Primary Target
nAChR

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

기타 정보

Dasgupta, X., et al., 2010. Proc. Natl. Acad. Sci.103, 6332.
Karavaev, N., et al., 2008. Neurosci. Behav. Physiol.38, 297.
Nelson, E., 1999. J. Physiol.516, 657.
Christ, D. 1980. Br. J. Pharmacol.69, 249.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable