420123-M

JNK Inhibitor II, Negative Control

The JNK Inhibitor II, Negative Control, also referenced under CAS 54642-23-8, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 동의어(들): JNK Inhibitor II, Negative Control, N¹-Methyl-1,9-pyrazoloanthrone
• 실험식(Hill 표기법): C₁₅H₁₀N₂O
• CAS Number: 54642-23-8
• Molecular Weight: 234.25
• MDL number: MFCD00003475
• UNSPSC 코드: 12352200

속성

• Quality Level: 100
• 분석: ≥97% (HPLC)
• 양식: solid
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; protect from light
• 색상: yellow
• solubility: DMSO: 10 mg/mL
• 저장 온도: −20°C

설명

일반 설명

A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC₅₀ = 18 µM and 24 µM, respectively) compared to SP600125 (IC₅₀ = 40 nM and 90 nM, respectively).

A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC₅₀ = 18 µM and 24 µM, respectively) compared to SP600125 (IC₅₀ = 40 nM and 90 nM, respectively).

생화학적/생리학적 작용

Primary Target
A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119)

Target IC₅₀: 18 µM and 24 µM against JNK2 and JNK3, respectively

경고

Toxicity: Standard Handling (A)

재구성

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable up to 3 months at -20°C.

기타 정보

Shin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta1589, 311.
Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA98, 13681.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable