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Merck
모든 사진(1)

문서

407140

Sigma-Aldrich

Anti-IP₃ Receptor Mouse mAb (IPR.1)

liquid, clone IPR.1, Calbiochem®

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About This Item

UNSPSC 코드:
12352203

생물학적 소스

mouse

Quality Level

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

IPR.1, monoclonal

형태

liquid

포함

≤0.1% sodium azide as preservative

종 반응성

rabbit, human, canine, mouse, rat, bovine, porcine

제조업체/상표

Calbiochem®

저장 조건

OK to freeze
avoid repeated freeze/thaw cycles

동형

IgG2b

배송 상태

wet ice

저장 온도

−20°C

타겟 번역 후 변형

unmodified

유전자 정보

human ... ITPR1(3708)
mouse ... Itpr1(16438)
rat ... Itpr1(25262)

일반 설명

Purified mouse monoclonal antibody. Recognizes all of the ~260 kDa IP3 receptor subtypes.
Recognizes all of the ~260 kDa IP3 receptor subtypes.
This Anti-IP₃ Receptor Mouse mAb (IPR.1) is validated for use in ELISA, FC, IF, IHC, IP, Radioimmunoassay, Immunoblotting for the detection of IP₃ Receptor.

면역원

a synthetic peptide (GGVGDVLRKPS) corresponding to amino acids near the C-terminus of the IP₃ receptor

애플리케이션

ELISA (1:1000)

Flow Cytometry (1:500)

Immunofluorescence (1:100)

Immunohistochemistry (1:100; see application references)

Immunoprecipitation (1:100; see application references)

Radioimmunoassay (1:5000)

Immunoblotting (see application references)

포장

Please refer to vial label for lot-specific concentration.

경고

Toxicity: Standard Handling (A)

물리적 형태

In 150 mM NaCl, 10 mM sodium phosphate, pH 7.5.

재구성

Following initial thaw, aliquot and freeze (-70°C).

분석 메모

Positive Control
Lymphocytes, macrophages, granulocytes, fibroblasts, epithelial and edothelial cells, skeletal muscle, cardiac muscle and brain tissue

기타 정보

Bourguignon, L.Y.W., et al. 1993. Cell Biol. Int.17, 751.
Bourguignon, L.Y.W., et al. 1993. J. Biol. Chem.268, 7290.
Specific for the C-terminal cytoplasmic domain of the IP3 receptor. For immunohistochemistry, this antibody requires FITC and confocal microscopy. Variables associated with assay conditions will dictate the proper working dilution.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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Endothelial cell (EC)-dependent vasodilation by proteinase-activated receptor 2 (PAR2) is preserved in small caliber arteries in disease states where vasodilation by muscarinic receptors is decreased. In this study, we identified and characterized the PAR2-mediated intracellular calcium (Ca(2+))-release mechanisms in EC
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The Journal of biological chemistry, 271(10), 5545-5551 (1996-03-08)
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The role of two-pore channel type 2 (TPC2, encoded by tcpn2)-mediated Ca2+ release was recently characterized in zebrafish during establishment of the early spinal circuitry, one of the key events in the coordination of neuromuscular activity. Here, we extend our

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