370654

PKG Inhibitor

The PKG Inhibitor controls the biological activity of PKG. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

• 동의어(들): PKG Inhibitor, Protein Kinase G Inhibitor, RKRARKE
• 실험식(Hill 표기법): C₃₈H₇₄N₁₈O₁₀
• Molecular Weight: 943.11
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥95% (HPLC)
• 형태: lyophilized
• 제조업체/상표: Calbiochem^®
• 저장 조건: OK to freeze; desiccated (hygroscopic)
• solubility: water: 1 mg/mL
• 배송 상태: ambient
• 저장 온도: −20°C

설명

일반 설명

A more specific, reversible, and substrate competitive inhibitor of protein kinase G (K_i = 86 µM) relative to protein kinase A (K_i = 550 µM). Sequence corresponds to a non-phosphorylatable analog (Ser³² to Ala³²) of histone H2B (amino acids 29-35).

A specific, reversible, and substrate competitive inhibitor of PKG (K_i = 86 µM) relative to PKA (K_i = 550 µM). Sequence corresponds to a non-phosphorylatable analog (Ser³² to Ala³²) of histone H2B (amino acids 29-35).

생화학적/생리학적 작용

Cell permeable: no

Product does not compete with ATP.

Reversible: yes

Target K_i: 86 µM against protein kinase G

포장

Yes

경고

Toxicity: Standard Handling (A)

서열

H-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH

기타 정보

Glass, D.B., et al. 1983. Biochem. J.213, 159.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable