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Merck
모든 사진(1)

문서

220551

Sigma-Aldrich

Chloramphenicol

Chloramphenicol, CAS 56-75-7, is a synthetic bacteriostatic antibiotic that inhibits the translation of RNA by blocking the peptidyltransferase reaction on ribosomes.

동의어(들):

Chloramphenicol

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About This Item

실험식(Hill 표기법):
C11H12Cl2N2O5
CAS Number:
Molecular Weight:
323.13
MDL number:
UNSPSC 코드:
12352200

Quality Level

분석

≥97% (by Assay)

형태

crystalline powder

제조업체/상표

Calbiochem®

저장 조건

OK to freeze

색상

gray to off-white

solubility

water: 2.5 mg/mL
methanol: 35 mg/mL
ethanol: soluble

배송 상태

ambient

저장 온도

10-30°C

InChI

1S/C11H12Cl2N2O5/c12-10(13)11(18)14-8(5-16)9(17)6-1-3-7(4-2-6)15(19)20/h1-4,8-10,16-17H,5H2,(H,14,18)

InChI key

WIIZWVCIJKGZOK-UHFFFAOYSA-N

관련 카테고리

일반 설명

Synthetic bacteriostatic antibiotic that inhibits the translation of RNA by blocking the peptidyltransferase reaction on ribosomes.
Synthetic bacteriostatic antibiotic that inhibits the translation of RNA to protein by binding to the 50S ribosomal subunit, blocking the peptidyl transferase reaction. Chloramphenicol resistance is encoded by the resistance gene cat, whose product, chloramphenicol acetyltransferase, inactivates the antibiotic via acetylation. Typically used at 30-50 µg/ml for selection of chloramphenicol-resistant Escherichia coli.

생화학적/생리학적 작용

Potency: ≥970 µg/mg
Primary Target
trasnslation of RNA

기타 정보

Lech, K., and Brent, R. 1995. in Current Protocols in Mol. Biol. Vol. 1, (Ausubel, F.M., et al., Eds.) John Wiley & Sons, New York.
Lu, J., and Jiang, C. 1993. Biochem. Biophys. Res. Commun.196, 12.
Saltarelli, M.J., et al. 1993. Virol.197, 35.
Holt, J.T. 1992. Ann. N.Y. Acad. Sci.660, 88.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, NY, p. 1.6, A.6.

법적 정보

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

Health hazardCorrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Carc. 2 - Eye Dam. 1 - Repr. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


시험 성적서(COA)

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