1.05980

D-Mannitol

EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, FCC, E 421

• 동의어(들): Mannite
• 실험식(Hill 표기법): C₆H₁₄O₆
• CAS Number: 69-65-8
• Molecular Weight: 182.17
• Beilstein: 1721898
• MDL number: MFCD00064287
• UNSPSC 코드: 12352201
• E 번호: E421
• EC 인덱스 번호: 200-711-8

속성

• Agency: BP; ChP; JP; Ph. Eur.; USP
• Quality Level: 500
• 규정 준수: FCC
• 제품 라인: EMPROVE^® ESSENTIAL
• 형태: fine powder
• autoignition temp.: 410 °C
• 효능: 13500 mg/kg LD₅₀, oral (Rat)
• 품질: E 421
• 입자 크기: (see specification)
• pH: 5-7 (20 °C, 100 g/L in H₂O)
• bp: 290-295 °C/4 hPa
• mp: 167-170 °C (lit.)
• solubility: 213 g/L
• 응용 분야: liquid formulation; pharmaceutical; semi-solid formulation; solid formulation
• 저장 온도: 2-25°C
• SMILES string: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
• InChI key: FBPFZTCFMRRESA-KVTDHHQDSA-N

설명

일반 설명

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

애플리케이션

Mannitol is widely used in pharmaceutical formulations and food applications, mainly as diluent and bulking agent in solid oral formulations such as tablets. For mannitols with DC properties or for a product specifically developed for wet granulation, please explore the Parteck^® range of products.

생화학적/생리학적 작용

A sugar alcohol sweet tastant. Used in sweetness inhibition studies.

법적 정보

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1