추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity purified immunoglobulin
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
human
제조업체/상표
Upstate®
기술
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... AKT3(10000)
특이성
Recognizes Akt3/PKBγ.
면역원
peptide corresponding to amino acids 119-131 of human Akt3/PKBgamma
애플리케이션
Anti-Akt3/PKBγ Antibody is an antibody against Akt3/PKBγ for use in IP & WB.
품질
routinely evaluated by immunoprecipitating active Akt3/PKBγ from IGF-I stimulated HEK293 cell lysates.
표적 설명
~60 kDa
결합
Replaces: AB3136
물리적 형태
Purified immunoglobulin in 30% glycerol, 0.07M Tris-glycine, pH 7.4, 0.105 M NaCl, 0.035% sodium azide as a preservative.
분석 메모
Control
IGF-I stimulated HEK293 cell lysates
IGF-I stimulated HEK293 cell lysates
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions
Katome, T., et al
The Journal of Biological Chemistry, 278, 28312-28323 (2003)
Demetris C Iacovides et al.
Molecular & cellular proteomics : MCP, 12(11), 3210-3220 (2013-08-10)
Breast cancer subtype-specific molecular variations can dramatically affect patient responses to existing therapies. It is thought that differentially phosphorylated protein isoforms might be a useful prognostic biomarker of drug response in the clinic. However, the accurate detection and quantitative analysis
Conrad P Hodgkinson et al.
Biochemistry, 41(32), 10351-10359 (2002-08-07)
Protein kinase B (PKB), also known as Akt, is a serine/threonine protein kinase controlled by insulin, various growth factors, and phosphatidylinositol 3-kinase. Full activation of the PKB enzyme requires phosphorylation of a threonine in the activation loop and a serine
François Fabi et al.
PloS one, 12(5), e0177387-e0177387 (2017-05-06)
Infertility is constantly increasing in Canada, where 16% of Canadian couples are experiencing difficulty conceiving. It is thought that infertility can emanate from the dysregulated communication between the embryo and the maternal endometrium. In order to allow for this window
Anna Joy et al.
Journal of neuro-oncology, 130(1), 43-52 (2016-10-21)
The growth factor receptor/PI3K/AKT pathway is an important drug target in many cancers including Glioblastoma. AKT, a key node in the pathway, has 3 isoforms, AKT1, AKT2 and AKT3. Here we investigate their role in GBM. We find each activated
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