추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
10C3, monoclonal
종 반응성
human
제조업체/상표
Upstate®
기술
activity assay: suitable
western blot: suitable
동형
IgG1
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
phosphorylation (pTyr1150/pTyr1151)
유전자 정보
human ... INSR(3643)
특이성
Recognizes phosphorylated domain of Insulin receptor on Tyrosine 1150/1151.
면역원
KLH-conjugated synthetic peptide encompassing the surrounding amino acids of Tyrosine 1150/1151 on phosphorylated insulin receptor.
애플리케이션
Detect phospho-Insulin Receptor (Tyr 1150/1151) using this Anti-phospho-Insulin Receptor (Tyr 1150/1151) Antibody, clone 10C3 validated for use in EA & WB.
품질
Routinely evaluated by immunoblot.
표적 설명
97 kDa
물리적 형태
Format: Purified
In 1 mL of PBS containing 0.09% sodium azide, PEG, and sucrose and 50% glycerol.
분석 메모
Control
Includes pervanadate treated HEK293 lysate as a positive control
Includes pervanadate treated HEK293 lysate as a positive control
법적 정보
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
10 - Combustible liquids
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Natalie N Rizk et al.
Fertility and sterility, 86(4 Suppl), 1217-1222 (2006-09-12)
To determine whether the insulin receptor (IR), insulin-like growth factor-I receptor (IGF-IR), and IGF-I are expressed differentially in fibroblasts isolated from normal peritoneal and adhesion tissue before and after 24-hour treatment with increasing glucose concentrations. Prospective experimental study. University medical
Qiu-yan Wang et al.
The FEBS journal, 274(2), 526-538 (2007-01-19)
Two H7721 human hepatocarcinoma cell lines showing moderate and high expression of alpha1,3-fucosyltransferase (FucT)-VII cDNA were established and designated FucTVII-M and FucTVII-H, respectively. In alpha1,3-FucT-VII-transfected cells, expression of insulin receptor (InR) alpha- and beta subunits and epidermal growth factor receptor
Rita Slaaby et al.
The Journal of biological chemistry, 281(36), 25869-25874 (2006-07-13)
Insulin receptor (IR) and insulin-like growth factor I receptor (IGF-IR) are both from the same subgroup of receptor tyrosine kinases that exist as covalently bound receptor dimers at the cell surface. For both IR and IGF-IR, the most described forms
Atsumi Tsuji-Hosokawa et al.
Pediatric diabetes, 18(8), 917-924 (2017-02-10)
Defects of the insulin receptor gene ( INSR ) cause wide spectra of congenital insulin resistance. Monoallelic defects result in milder insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN, type A). Whereas, leprechaunism (Donahue syndrome), the most severe condition with lethality
Adrián Martín-Segura et al.
Aging cell, 18(3), e12932-e12932 (2019-03-19)
In the brain, insulin plays an important role in cognitive processes. During aging, these faculties decline, as does insulin signaling. The mechanism behind this last phenomenon is unclear. In recent studies, we reported that the mild and gradual loss of
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