P-066

Pregabalin solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 실험식(Hill 표기법): C₈H₁₇NO₂
• CAS Number: 148553-50-8
• Molecular Weight: 159.23
• EC Number: 200-659-6
• MDL number: MFCD00906155
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329820047
• NACRES: NA.24

속성

• Grade: certified reference material
• 형태: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 1.0 mg/mL in methanol
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: clinical testing
• 형식: single component solution
• 배송 상태: wet ice
• 저장 온도: −20°C
• SMILES string: CC(CC([H])(CN)CC(O)=O)C
• InChI: 1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)
• InChI key: AYXYPKUFHZROOJ-UHFFFAOYSA-N

설명

일반 설명

Sold under the trade name Lyrica^®, pregabalin is an antiepileptic drug used for treatment of seizures, fibromyalgia, diabetic peripheral neuropathy, generalized anxiety disorder, and chronic neuropathic pain. This certified reference standard is suitable for pregabalin GC/MS or LC/MS applications from forensic analysis, clinical toxicology and pain prescription monitoring to urine drug testing.

애플리케이션

• Evaluation of Pregabalin and Dexamethasone Coadministration: This study assesses the effects of Pregabalin combined with dexamethasone on preemptive multimodal analgesia and anxiety management during third molar surgeries. The trial highlighted its potential to significantly improve patient outcomes in dental procedures (Diniz et al., 2024).


• Interactions with Antiepileptic Drugs: This article explores how Pregabalin interacts with other antiepileptic drugs when used for primary and secondary stroke prevention, particularly focusing on its compatibility and potential interactions in clinical settings (Stöllberger & Finsterer, 2024).


• Molecular Docking Analysis: This research utilizes molecular docking techniques to analyze Pregabalin and other marine compounds targeting voltage-gated calcium channels, aiming to identify potential anti-epileptic molecules (Sheokand et al., 2024).


• Management of Neuropathic Pain in Cats: Focused on veterinary medicine, this review discusses the mechanisms of neuropathic pain in cats and how Pregabalin, among other treatments, can be used for multimodal pain management (Rusbridge, 2024).


• Pharmacotherapy and Noninvasive Neurostimulation: This article reviews current pharmacotherapies including Pregabalin and noninvasive neurostimulation techniques for treating neuropathic pain, providing an overview of effective pain management strategies (Spagna & Attal, 2024).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Lyrica is a registered trademark of C.P. Pharmaceuticals International C.V.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup