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Merck
모든 사진(1)

문서

L-002

Supelco

LSD-D3 solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

동의어(들):

Lysergic acid diethylamide-D3

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C20H22N3OD3
CAS Number:
Molecular Weight:
326.45
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material

형태

liquid

특징

Snap-N-Spike®/Snap-N-Shoot®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

drug control

Narcotic Licence Schedule D (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIA (Portugal)

농도

100 μg/mL in acetonitrile

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

forensics and toxicology

형식

single component solution

저장 온도

2-8°C

SMILES string

O=C(N(CC)CC)[C@H]1CN(C([2H])([2H])[2H])[C@](C2=C1)([H])CC3=CNC4=C3C2=CC=C4

InChI

1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1/i3D3

InChI key

VAYOSLLFUXYJDT-WABLSUFGSA-N

일반 설명

LSD, or lysergic acid diethylamide, is an illicit psychedelic drug with potent hallucinogenic effects such as altered thinking processes, closed- and open-eye visuals, synesthesia and an altered sense of time. This internal standard is suitable for LSD testing or isotope dilution methods by GC/MS or LC/MS for urine drug testing, clinical toxicology, or forensic analysis.

애플리케이션


  • Hydrocodone-D₃ Analytical Standard Applications: Hydrocodone-D₃ serves as a crucial analytical standard in forensic toxicology, enabling precise quantification and validation of hydrocoDonein biological samples. Its stable isotope-labeled structure is essential for mass spectrometry, providing accurate measurement standards for opioid research and ensuring reliability in legal and clinical settings (Gent et al., 2024).

  • Role in Opioid Research: The compound is instrumental in opioid research, particularly in studying hydrocodone′s pharmacokinetics and dynamics. As a deuterated internal standard, Hydrocodone-D₃ enhances the specificity and sensitivity of assays designed to investigate opioid metabolism and its interactions within the human body (Upadhyay et al., 2024).

  • Biotech Research Chemical Standard: In biotechnology, Hydrocodone-D₃ is used for developing new drug formulations and therapeutic approaches. Its application extends to creating more effective opioid medications with controlled release properties, aimed at reducing dependency and side effects (Senta et al., 2020).

  • Pharmacokinetic Studies: This solution is pivotal in pharmacokinetic studies where researchers assess the absorption, distribution, metabolism, and excretion (ADME) of hydrocodone. By using Hydrocodone-D₃, scientists can track and understand the drug′s behavior in the body more accurately, leading to improved dosing guidelines and safer drug use (Dias Neves et al., 2024).

  • Advancements in Bioanalysis: Hydrocodone-D₃ is also used in advanced bioanalytical research to explore new methodologies for drug testing and monitoring. It acts as a reference point in developing novel detection techniques that are crucial for clinical diagnostics and therapeutic drug monitoring (Zhuang et al., 2024).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

픽토그램

FlameExclamation mark

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

35.6 °F - closed cup

Flash Point (°C)

2 °C - closed cup


시험 성적서(COA)

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문서 라이브러리 방문

Justyna McIntyre et al.
The Journal of biological chemistry, 290(45), 27332-27344 (2015-09-16)
Human DNA polymerases (pols) η and ι are Y-family DNA polymerase paralogs that facilitate translesion synthesis past damaged DNA. Both polη and polι can be monoubiquitinated in vivo. Polη has been shown to be ubiquitinated at one primary site. When

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