C-007

Codeine-D₃ solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 실험식(Hill 표기법): C₁₈H₁₈D₃NO₃
• CAS Number: 70420-71-2
• Molecular Weight: 302.38
• EC Number: 200-659-6
• MDL number: MFCD01075373
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329774760
• NACRES: NA.24

속성

• Grade: certified reference material
• 형태: liquid
• 특징: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 농도: 1.0 mg/mL in methanol
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: forensics and toxicology
• 형식: single component solution
• 저장 온도: −20°C
• SMILES string: [2H]C([2H])([2H])N1CC[C@]23[C@H]4Oc5c(OC)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35
• InChI: 1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3-6,11-13,17,20H,7-9H2,1-2H3/t11-,12+,13-,17-,18-/m0/s1/i1D3
• InChI key: OROGSEYTTFOCAN-SBGSAQJDSA-N

설명

일반 설명

Codeine-D₃ is a stable-labeled internal standard suitable for many LC/MS or GC/MS testing applications including pain prescription monitoring, forensic analysis, clinical toxicology, urine drug testing or isotope dilution methods. Codeine is an opiate used for its analgesic, antitussive, and sedative properties and is the second-most predominant alkaloid in opium. Since opiate drugs are classified as controlled substances, Cerilliant offers most opiate reference standards as DEA-exempt solutions for added convenience.

애플리케이션

<ul>
<li><strong>Codeine-D3 analytical standard in opioid detection:</strong> Codeine-D3 is used as an internal standard for the accurate determination of opioids in blood and pericardial fluid, enhancing forensic and clinical toxicology analyses (Ferreira et al., 2020).</li>
<li><strong>Deuterated codeine for research in plasma opioid quantification:</strong> Comparison of mass spectrometry techniques using Codeine-D3 to quantify opioids in human plasma highlights its application in enhancing the sensitivity and specificity of pharmacokinetic studies (Viaene et al., 2016).</li>
<li><strong>Codeine isotopic label in urinary opiate analysis:</strong> An LC-MS method was validated using Codeine-D3, proving its efficacy in the accurate determination of urinary opiate metabolites, thereby supporting drug monitoring and compliance testing (Svensson et al., 2007).</li>
<li><strong>High-purity Codeine-D3 for biochemistry research:</strong> Codeine-D3 was crucial in validating a direct injection electrospray LC-MS/MS technique for opiates in urine drug testing, underscoring its utility in clinical diagnostics and forensic investigations (Gustavsson et al., 2007).</li>
</ul>

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 표적 기관: Eyes,Central nervous system
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup