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Merck
모든 사진(1)

문서

B-001

Supelco

Benzoylecgonine-d3 solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

동의어(들):

Benzoylecgonine-N-methyl-d3 solution

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About This Item

실험식(Hill 표기법):
C16D3H16NO4
CAS Number:
Molecular Weight:
292.34
EC Number:
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

certified reference material

형태

liquid

특징

SNAP-N-SPIKE®, SNAP-N-SHOOT®

포장

ampule of 1 mL

제조업체/상표

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

농도

100 μg/mL in methanol

기술

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

응용 분야

forensics and toxicology

형식

single component solution

질량 이동

M+3

배송 상태

wet ice

저장 온도

−20°C

SMILES string

[2H]C([2H])([2H])N1[C@H]2CC[C@@H]1[C@H]([C@H](C2)OC(=O)c3ccccc3)C(O)=O

InChI

1S/C16H19NO4/c1-17-11-7-8-12(17)14(15(18)19)13(9-11)21-16(20)10-5-3-2-4-6-10/h2-6,11-14H,7-9H2,1H3,(H,18,19)/t11-,12+,13-,14+/m0/s1/i1D3

InChI key

GVGYEFKIHJTNQZ-GZBWLTEMSA-N

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일반 설명

A stable-labeled internal standard suitable for isotope dilution methods or benzoylecgonine testing in urine, saliva, blood, or hair by GC/MS or LC/MS for applications in clinical toxicology, urine drug testing, pain prescription monitoring or forensic analysis. Benzoylecgonine is the primary metabolite of cocaine and a major biomarker for determination of cocaine use.

애플리케이션


  • Mass Spectrometry Internal Standard: Benzoylecgonine-d₃ is utilized as a robust internal standard in mass spectrometry to enhance the accuracy and precision of quantitative analysis of cocaine metabolites in clinical toxicology studies, providing crucial data for forensic and clinical applications (Handley et al., 2019).

  • Forensic Toxicology Research: The application of Benzoylecgonine-d₃ in gas chromatography-mass spectrometry (GC-MS) underscores its value in the forensic analysis of cocaine and its metabolites in biological samples, offering reliable quantification essential for legal and medical investigations (Fleming et al., 2010).

  • LC-MS/MS Quantitative Analysis: Benzoylecgonine-d₃ serves as a critical component in developing validated LC-MS/MS methodologies for drug testing, ensuring the traceability and reproducibility required in doping control and therapeutic drug monitoring (Lin et al., 2001).

  • Pharmacokinetic Studies: The use of stable isotope-labeled Benzoylecgonine-d₃ enables detailed pharmacokinetic studies, helping to understand the metabolism of cocaine and assess the impact of various physiological and pathological conditions on drug metabolism (Lin et al., 2001).

  • Drug Metabolism Analysis: In forensic science, Benzoylecgonine-d₃ is crucial for developing sensitive and selective analytical methods for detecting and quantifying cocaine use, supporting both clinical diagnostics and legal proceedings (Hall et al., 1999).


법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

관련 제품

제품 번호
설명
가격

픽토그램

FlameSkull and crossbonesHealth hazard

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

표적 기관

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point (°F)

49.5 °F - closed cup

Flash Point (°C)

9.7 °C - closed cup


시험 성적서(COA)

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