A-158

Amoxapine-D₈ solution

100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• 실험식(Hill 표기법): C₁₇H₈D₈ClN₃O
• CAS Number: 1189671-27-9
• Molecular Weight: 321.83
• UNSPSC 코드: 41116107
• NACRES: NA.24

속성

• Grade: certified reference material
• Quality Level: 300
• 형태: liquid
• 특징: Snap-N-Spike^®/Snap-N-Shoot^®
• 포장: ampule of 1 mL
• 제조업체/상표: Cerilliant^®
• 농도: 100 μg/mL in methanol
• 기술: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 응용 분야: clinical testing
• 형식: single component solution
• 저장 온도: −20°C
• InChI: 1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2/i7D2,8D2,9D2,10D2
• InChI key: QWGDMFLQWFTERH-UFBJYANTSA-N

설명

일반 설명

This stable-labeled internal standard is suitable for quantification of amoxopine by LC-MS/MS or GC/MS for applications in clinical toxicology, forensic analysis, urine drug testing, pharmaceutical research, or therapeutic drug monitoring. Amoxopine is a tetracyclic antidepressant sold under notable trade names including Asendin^;, Asendis^;, Defanyl^; and Demolox^; for the treatment of major depressive disorder.

애플리케이션

• Amoxapine-D8 internal standard: Utilization of Amoxapine-D8 as an internal standard in mass spectrometry significantly enhances analytical accuracy, particularly in bioanalytical assays aimed at understanding the pharmacokinetics and metabolite profiling of Amoxapine. This application is essential for ensuring precise measurement in pharmaceutical research (Lin H et al., 2024).
• Stable isotope-labeled Amoxapine for biochemical studies: The use of stable isotope-labeled Amoxapine-D8 enables detailed studies on its metabolism and interaction with biological systems. This approach is crucial for developing a deeper understanding of its biochemical pathways and potential therapeutic effects (Al-Fakhrany OM et al., 2024).
• Amoxapine-D8 in pharmacological research: Research involving Amoxapine-D8 explores its pharmacological actions, especially its utility in treating conditions like depression and anxiety. By using deuterated versions, researchers can gain insights into the drug′s behavior in the body, improving the development of effective therapeutic regimens (Ainousah BE et al., 2024).
• High-purity Amoxapine-D8 for mass spectrometry: High-purity Amoxapine-D8 is critical for mass spectrometry applications where accuracy and minimal background noise are paramount. This purity level facilitates the study of complex biological samples, enabling more precise and reliable analytical outcomes (Sharma MK et al., 2024).

법적 정보

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS02,GHS06,GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H225,H301 + H311 + H331,H370
• 예방조치 성명서: P210 - P280 - P302 + P352 + P312 - P304 + P340 + P311 - P370 + P378 - P403 + P235
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Storage Class Code: 3 - Flammable liquids
• Flash Point (°F): 49.5 °F - closed cup
• Flash Point (°C): 9.7 °C - closed cup