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Merck
모든 사진(1)

문서

860592P

Avanti

24:0 SM

Avanti Research - A Croda Brand 860592P, powder

동의어(들):

N-lignoceroyl-D-erythro-sphingosylphosphorylcholine

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About This Item

실험식(Hill 표기법):
C47H95N2O6P
CAS Number:
Molecular Weight:
815.24
UNSPSC 코드:
12352211
NACRES:
NA.25

형태

powder

포장

pkg of 1 × 10 mg (860592P-10mg)
pkg of 1 × 5 mg (860592P-5mg)

제조업체/상표

Avanti Research - A Croda Brand 860592P

지질 유형

sphingolipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)COP([O-])(OCC[N+](C)(C)C)=O

일반 설명

d-erythro (2S, 3R) sphingomyelin (C24:0-SM) is a synthetic sphingomyelin with acyl chain comprising 24 carbon atom. It is produced by the acylation of D-erythro-sphingosylphosphorylcholine. Sphingomyelin is a key constituent of mammalian cell plasma membranes. It is mainly found at high concentrations in the myelin sheaths of nerve cells, in brain, eye lens and red blood cells. SM have asymmetric molecular structure and high hydrogen-bonding capacity.

애플리케이션

24:0 sphingomyelin (SM) is suitable to study its thermotropic and mechanical properties by using differential scanning calorimetry. It is also suitable for use as a lipid standard in ultrafast liquid chromatography−tandem mass spectrometry.

생화학적/생리학적 작용

Sphingomyelin (SM) are involved in the formation of functional domains in the membrane bilayer. It also acts as a precursor for sphingolipid signaling molecules including, ceramides and other sphingolipid metabolites.

포장

5 mL Amber Glass Screw Cap Vial (860592P-10mg)
5 mL Amber Glass Screw Cap Vial (860592P-5mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


시험 성적서(COA)

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문서 라이브러리 방문

Mechanical properties of milk sphingomyelin bilayer membranes in the gel phase: Effects of naturally complex heterogeneity, saturation and acyl chain length investigated on liposomes using AFM
Et-Thakafy O, et al.
Chemistry and Physics of Lipids, 210, 47-59 (2018)
Phase transitions of highly asymmetric chain-length N-lignocerylsphingomyelin (C24: 0-SM) bilayer
Ohtaka H, et al.
Journal of Thermal Analysis and Calorimetry, 113(3), 1593-1602 (2013)
Very-long-chain fatty acid sphingomyelin in nuclear lipid microdomains of hepatocytes and hepatoma cells: can the exchange from C24: 0 to C16: 0 affect signal proteins and vitamin D receptor?
Lazzarini A, et al.
Molecular Biology of the Cell, 26(13), 2418-2425 (2015)
Elisabetta Albi et al.
International journal of molecular sciences, 15(7), 11555-11565 (2014-07-01)
Proliferating thyroid cells are more sensitive to UV-C radiations than quiescent cells. The effect is mediated by nuclear phosphatidylcholine and sphingomyelin metabolism. It was demonstrated that proton beams arrest cell growth and stimulate apoptosis but until now there have been
Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor

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