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Merck
모든 사진(2)

문서

840861P

Avanti

18:0-18:1 PA

1-stearoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt), powder

동의어(들):

1-octadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphate (sodium salt); SOPA; PA(18:0/18:1(9Z))

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About This Item

실험식(Hill 표기법):
C39H74O8PNa
CAS Number:
Molecular Weight:
724.96
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

형태

powder

포장

pkg of 1 × 25 mg (840861P-25mg)

제조업체/상표

Avanti Research - A Croda Brand 840861P

지질 유형

cardiolipins
phospholipids

배송 상태

dry ice

저장 온도

−20°C

SMILES string

[H][C@@](COP([O-])(O)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C39H75O8P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(40)45-35-37(36-46-48(42,43)44)47-39(41)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h18,20,37H,3-17,19,21-36H2,1-2H3,(H2,42,43,44);/q;+1/p-1/b20-18-;/t37-;/m1./s1

InChI key

QTWIAVIWKTYOHY-HTNAYUJGSA-M

일반 설명

Phosphatidic acid (PA), a phospholipid is a minor component of the phospholipid pool. It is an important constituent of cell membranes.

애플리케이션

18:0-18:1 PA (1-stearoyl-2-oleoyl-sn-glycero-3-phosphate (sodium salt)) may be used as a phosphatidic acid (PA) standard to identify the corresponding radiolabeled PA on the thin-layer chromatography (TLC). It may be also used in vesicles for experimental validation in order to identify novel phospholipids capable of inhibiting cellular membrane transportation by (ATP)-binding cassette P-glycoprotein (P-gp).

생화학적/생리학적 작용

Phosphatidic acid (PA) serves as a lipid messenger and a signaling lipid.

포장

5 mL Clear Glass Sealed Ampule (840861P-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Y Liu et al.
American journal of physiology. Lung cellular and molecular physiology, 295(3), L471-L478 (2008-07-16)
We have previously reported the participation of mitogen-activated protein, Rho, and phosphoinositide-3 (PI3) kinases in separate pathways in serotonin (5-HT)-induced proliferation of pulmonary artery smooth muscle cells (SMCs). In this study, we investigated the possible participation of phospholipase D (PLD)
Guillermo Escalante et al.
Journal of the International Society of Sports Nutrition, 13, 24-24 (2016-06-09)
Phosphatidic acid (PA) is a lipid messenger that has been shown to increase muscle protein synthesis via signaling stimulation of the mammalian target of rapamycin (mTOR). MaxxTOR® (MT) is a supplement that contains PA as the main active ingredient but
Xavier Lucas et al.
PloS one, 8(4), e60679-e60679 (2013-04-18)
P-glycoprotein is capable of effluxing a broad range of cytosolic and membrane penetrating xenobiotic substrates, thus leading to multi-drug resistance and posing a threat for the therapeutic treatment of several diseases, including cancer and central nervous disorders. Herein, a virtual

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