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Merck
모든 사진(2)

문서

700048P

Avanti

24(R/S),25-epoxycholesterol-d6

Avanti Research - A Croda Brand

동의어(들):

26,26,26,27,27,27-hexadeutero-24,25-epoxycholesterol

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About This Item

실험식(Hill 표기법):
C27H38O2D6
CAS Number:
Molecular Weight:
406.67
UNSPSC 코드:
41116107
NACRES:
NA.25

설명

24(R/S),25-epoxycholesterol-d6

분석

>99% (TLC)

형태

powder

포장

pkg of 1 × 1 mg (700048P-1mg)

제조업체/상표

Avanti Research - A Croda Brand

배송 상태

dry ice

저장 온도

−20°C

일반 설명

24(R/S),25-epoxycholesterol-d6 is a deuterated side-chain substituted oxysterol.

애플리케이션

24(R/S),25-epoxycholesterol-d6 has been used as a primary and deuterated surrogate sterol standard in the quantitative analysis of extracted sterol samples from cultured cells and tissues.

생화학적/생리학적 작용

24(S),25-epoxycholesterol maintains cholesterol homeostasis. It modulates hepatic cholesterol metabolism in vivo. 24(S),25-epoxycholesterol is synthesized in the mevalonate pathway. It inhibits sterol regulatory element-binding protein (SREBP) activation.
Deuterated sterol plays a vital role in chemical and biochemical research. It is used as a mechanistic tracer to study the role of steroid hormones in the function and modulation of several physiological processes. Deuterated sterol is also used as reference standards for mass spectrometry. 24(R/S),25-epoxycholesterol-d6 is a deuterium labeled sterol.

포장

5 mL Amber Glass Screw Cap Vial (700048P-1mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids


시험 성적서(COA)

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문서 라이브러리 방문

Site-specific synthesis and application of Deuterium-Labeled sterols
Muchalski H, et al.
Archive for Organic Chemistry (2017)
24 (S), 25-epoxycholesterol: a messenger for cholesterol homeostasis
Brown AJ
The International Journal of Biochemistry & Cell Biology, 41(4), 744-747 (2019)
Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry
McDonald J, et al.
Test, 432, 145-170 (2007)
Jeffrey G McDonald et al.
Methods in enzymology, 432, 145-170 (2007-10-24)
We describe the development of a high performance liquid chromatography mass spectrometry (HPLC-MS) method that allows the identification and quantitation of sterols in mammalian cells and tissues. Bulk lipids are extracted from biological samples by a modified Bligh/Dyer procedure in

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