QBD10007

Biotin-dPEG^®₂₄-TFP ester

• 동의어(들): Polyethylene glycol
• 실험식(Hill 표기법): C₆₇H₁₁₇F₄N₃O₂₈S
• Molecular Weight: 1520.71
• UNSPSC 코드: 12352108
• PubChem Substance ID: 329823871
• NACRES: NA.22

속성

• 분석: >90%
• 형태: solid or viscous liquid
• 반응 적합성: reaction type: Biotinylations; reaction type: Biotinylations; reactivity: amine reactive; reagent type: cross-linking reagent
• 폴리머 구조: shape: linear; functionality: monofunctional
• 배송 상태: ambient
• 저장 온도: −20°C
• SMILES string: O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O

설명

특징 및 장점

The Biotin-dPEG^®₂₄-TFP ester has 2,3,5,6-tetrafluorophenyl (TFP) moiety which hydrolyze more slowly than NHS esters in aqueous media and are more reactive towards amines than NHS esters. The single molecular weight Biotin-dPEG^®₂₄-TFP ester has a long spacer of precise length (99.3 Å) between the biotin moiety and the labeled molecule. This dPEG spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

법적 정보

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable