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Merck
모든 사진(1)

문서

ALD00032

Sigma-Aldrich

1-(Oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one

동의어(들):

1-(Oxazolo[4,5-b]pyridin-2-yl)-1-oxo-6-phenylhexane, 1-Oxazolo[4,5-b]pyridin-2-yl-6-phenyl-1-hexanone, OL-100

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About This Item

실험식(Hill 표기법):
C18H18N2O2
CAS Number:
Molecular Weight:
294.35
UNSPSC 코드:
12352200
PubChem Substance ID:
NACRES:
NA.22

형태

solid

저장 온도

−20°C

SMILES string

O=C(C1=NC2=C(C=CC=N2)O1)CCCCCC3=CC=CC=C3

InChI

1S/2C18H18N2O2/c2*21-15(18-20-17-16(22-18)12-7-13-19-17)11-6-2-5-10-14-8-3-1-4-9-14/h2*1,3-4,7-9,12-13H,2,5-6,10-11H2

InChI key

LFAKEBRRAYWLPI-UHFFFAOYSA-N

애플리케이션

Inhibitor of Fatty acid amide hydrolase (FAAH); a serine hydrolase resposible for the transformation of anandamide to arachidonic acid

Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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관련 콘텐츠

As the exploration of the properties of complex natural products becomes increasingly more sophisticated with the technological advances being made in their screening and evaluation and as structural details of their interaction with biological targets becomes more accessible, the importance and opportunities for providing unique solutions to complex biological problems has grown. The Boger Lab addresses these challenging problems by understanding the complex solutions and subtle design elements that nature has provided in the form of a natural product and work to extend the solution through rational design elements to provide more selective, more efficacious, or more potent agents designed specifically for the problem or target under investigation. The resulting efforts have reduced many difficult or intractable synthetic challenges to manageable problems providing an approach not only to the natural product but one capable of simple extrapolation to a series of structural analogs with improved selectivity and efficacy.

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