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Merck
모든 사진(1)

문서

911259

Sigma-Aldrich

Poly(ethylene glycol) linear dendrimer

carboxyl terminated, PEG Mn 10k, generation 3

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About This Item

실험식(Hill 표기법):
C588H1086O318
Molecular Weight:
13244.72
UNSPSC 코드:
12352120
NACRES:
NA.23

형태

solid

분자량

PEG Mn 10k
PEG average Mn 10,000
generation 3

표면기 개수

16

색상

white to off-white

작용기

carboxylic acid

저장 온도

−20°C

일반 설명

  • Polymer architecture: PEG-core dendrimer
  • End Group Functionality: Carboxylic acid
  • Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid

애플리케이션

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolyzable linker allows for degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. This dendritic polymer is biocompatible, biodegradable, and suitable for biomedical applications. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, enabling use for advanced drug delivery systems or for drug targeting. The carboxylic acid-functionalized corona can be readily used for bioconjugation reactions.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

문서

Dendritic molecules' biomedical applications, particularly bis-MPA dendritic scaffolds, hold promise for drug delivery.

Dendrimers, polymer nanostructures, are synthesized for specific purposes by manipulating critical nanoscale design parameters (CNDPs).

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