901369

Polyester bis-MPA dendron

16 azide, 1 NHBoc (core), generation 4

• 동의어(들): Bis-MPA dendron, PFd-G4-BOCNH-Azide
• 실험식(Hill 표기법): C₁₈₇H₂₉₅N₄₉O₆₉
• Molecular Weight: 4333.63
• UNSPSC 코드: 12162002
• NACRES: NA.23

속성

• 형태: solid
• 재고 정보: available only in USA
• 색상: white to off-white
• 저장 온도: −20°C

설명

일반 설명

• Polymer architecture: Dendron
• Generation: 4
• Core functional group: Boc-protected amine
• End Group Functionality: Azide
• No. Surface Groups: 16
• Calculated Mol. Wt.: 4333.69 g/mol
• Boc : tert-Butyloxycarbonyl
• Bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid

애플리케이션

Bis-MPA (or 2,2-bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from Bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. The azide-functionalized dendrimers can be readily functionalized using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC) or strain-promoted alkyne-azide cycloaddition (SPAAC). Additionally, the amine-functionalized core can be readily used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications.

안전성 정보

• 픽토그램: GHS02
• 신호어: Danger
• 유해 및 위험 성명서: H242
• 예방조치 성명서: P210 - P234 - P235 - P240 - P370 + P378 - P403
• Hazard Classifications: Self-react. C
• Storage Class Code: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable