760935

Poly(ethylene glycol), 4 acetylene dendron, generation 1

average M_n 20,000

• 동의어(들): Bis-MPA poly(ethylene glycol), Bis[2,2-bis(hydroxymethyl)propanoic acid] PEG, Dendron functionalized PEG acetylene, generation 1, PEG-20,000, PFD-G1-PEG20k-Acetylene
• UNSPSC 코드: 12162002
• NACRES: NA.23

속성

• 설명: esterified with 4 acetylene groups
• 양식: solid
• 분자량: PEG average M_n 20,000 (n~450); average M_n 20,000
• 특징: generation 1
• 표면기 개수: 4
• mp: 56-60
• 작용기: alkyne

설명

일반 설명

Dendrimers and dendrons are symmetrically branched polymer structures that possess a well-defined spatial distribution of functional groups.[1] Dendrimers are chemically modified by attaching poly ethylene glycol (PEG) molecule to increase its solubility and prolong circulation half-life.[2]"Clickable groups", such as primary acetylenes, are introduced to the mono dispersed dendritic structures, using "click" chemistry. These acetylene groups, attached to Bis-MPA based dendrons, allow it to form the conjugates with bioactive moieties such as carbohydrate, fluorescent dyes, disaccharides etc.[3][4]

애플리케이션

The proposed uses are

• as an efficient drug delivery system.
• In vitro toxicological studies
• In vivo via radionuclide labeling and optical imaging
• Biosensors
• Dip pen nanolithography[1][4]

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable