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Merck
모든 사진(1)

문서

652369

Sigma-Aldrich

1-Amino-1-cyclobutanecarboxylic acid

97%

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About This Item

Linear Formula:
H2NC4H6CO2H
CAS Number:
Molecular Weight:
115.13
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.22

분석

97%

형태

solid

반응 적합성

reaction type: solution phase peptide synthesis

mp

261 °C (dec.) (lit.)

응용 분야

peptide synthesis

SMILES string

NC1(CCC1)C(O)=O

InChI

1S/C5H9NO2/c6-5(4(7)8)2-1-3-5/h1-3,6H2,(H,7,8)

InChI key

FVTVMQPGKVHSEY-UHFFFAOYSA-N

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픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

1-Aminocyclobutane-1-carboxylate (ACBC): a specific antagonist of the N-methyl-D-aspartate receptor coupled glycine receptor.
W F Hood et al.
European journal of pharmacology, 161(2-3), 281-282 (1989-02-28)
I Varela et al.
The Biochemical journal, 267(2), 541-544 (1990-04-15)
The ability of the insulin-induced phospho-oligosaccharide to stimulate amino acid transport was studied in isolated rat hepatocytes. At low alpha-aminoisobutyric acid concentrations (0.1 mM), both 100 nM-insulin and 10 microM-phospho-oligosaccharide doubled amino acid uptake after 2 h of incubation. This
Y Gaoni et al.
Journal of medicinal chemistry, 37(25), 4288-4296 (1994-12-09)
A range of cis- and trans-3-substituted 1-aminocyclobutane-1-carboxylic acids has been synthesized and evaluated for antagonism at excitatory amino acid receptor sites and for anticonvulsant activity. Potent and selective antagonist activity at N-methyl-D-aspartate (NMDA) receptor sites in neonatal rat motoneurones was
T S Rao et al.
Neuropharmacology, 29(3), 305-309 (1990-03-01)
Following intravenous administration, 1-aminocyclobutane-1-carboxylate (ACBC, 100 mg/kg), a N-methyl-D-aspartate (NMDA)-associated glycine receptor antagonist, was eliminated with a T1/2 of 5 min in mouse brain and 4 min in rat cerebrospinal fluid (CSF). 1-Aminocyclopropane-1-carboxylate (ACC), a NMDA-associated glycine receptor agonist, was
G B Watson et al.
Neuropharmacology, 29(8), 727-730 (1990-08-01)
In Xenopus oocytes, injected with mRNA from the brain of the rat, the characteristics of the cyclic homologues of glycine, ACPC, ACBC and cycloleucine have been examined. 1-Aminocyclopropane-1-carboxylate was a potent agonist at the NMDA-associated glycine site (EC50 = 0.09

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