498327

Ethyl 2-fluoroacetoacetate

• 동의어(들): 2-Fluoro-3-oxobutanoic acid ethyl ester, Ethyl 2-fluoro-3-oxobutanoate, Ethyl 2-fluoro-3-oxobutyrate, NSC 24563
• Linear Formula: CH₃COCH(F)CO₂C₂H₅
• CAS Number: 1522-41-4
• Molecular Weight: 148.13
• MDL number: MFCD00215830
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24873190

속성

• refractive index: n20/D 1.414 (lit.)
• bp: 183 °C (lit.)
• density: 1.181 g/mL at 25 °C (lit.)
• SMILES string: CCOC(=O)C(F)C(C)=O
• InChI: 1S/C6H9FO3/c1-3-10-6(9)5(7)4(2)8/h5H,3H2,1-2H3
• InChI key: SHTFQLHOTAJQRJ-UHFFFAOYSA-N

설명

일반 설명

Ethyl 2-fluoroacetoacetate is an α-fluorinated β-keto ester that can be prepared by the fluorination of ethyl acetoacetate.

애플리케이션

Ethyl 2-fluoroacetoacetate may be used in the preparation of:

• δ-keto-β-hydroxy-α-fluoro esters
• fluorinated [1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-ones
• fluorinated [1,2,4]triazolo[5,1-c][1,2,4]triazin-4(1H)-ones
• 4-fluorofarnesol

Reactant for:

• Michael addition-induced cyclization reaction
• Asymmetric Mannich reaction
• Enantioselective organocatalytic conjugate addition

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 194.0 °F - closed cup
• Flash Point (°C): 90 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves, type ABEK (EN14387) respirator filter