모든 사진(1)
About This Item
Linear Formula:
O2NC6H4SO2C6H5
CAS Number:
Molecular Weight:
263.27
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
분석
97%
mp
145-148 °C (lit.)
SMILES string
[O-][N+](=O)c1ccccc1S(=O)(=O)c2ccccc2
InChI
1S/C12H9NO4S/c14-13(15)11-8-4-5-9-12(11)18(16,17)10-6-2-1-3-7-10/h1-9H
InChI key
GKNMUCPEXSCGKC-UHFFFAOYSA-N
일반 설명
2-Nitrophenyl phenyl sulfone (NPPS) is a substituted diarylsulfone derivative. It has been reported to protect the human CEM-SS lymphoblastoid cells from the cytopathic effects of HIV-1 in cell culture. Structure-activity relationship of 2-nitrophenyl phenyl sulfone has been studied.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
가장 최신 버전 중 하나를 선택하세요:
J B McMahon et al.
Antimicrobial agents and chemotherapy, 37(4), 754-760 (1993-04-01)
A series of variously substituted diarylsulfones and related derivatives were found to prevent human immunodeficiency virus type 1 (HIV-1) replication and HIV-1-induced cell killing in vitro. One of the more potent derivatives, 2-nitrophenyl phenyl sulfone (NPPS), completely protected human CEM-SS
M Artico et al.
Archiv der Pharmazie, 328(3), 223-229 (1995-03-01)
Various aryl 1-pyrryl sulfones were synthesized and tested as inhibitors of HIV-1. 2-Nitrophenyl-2-ethoxycarbonyl-1-pyrryl sulfone, the most active among test derivatives, was selected as lead compound of the aryl pyrryl sulfone series. The in vitro anti-HIV-1 activity and cytotoxicity of 41
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.