407135

(1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol

97%

• 동의어(들): (+)-DBNE, N,N-Dibutyl-L-(+)-norephedrine
• Linear Formula: [CH₃(CH₂)₃]₂NCH(CH₃)CH(C₆H₅)OH
• CAS Number: 115651-77-9
• Molecular Weight: 263.42
• MDL number: MFCD00142689
• UNSPSC 코드: 12352116
• PubChem Substance ID: 24865427

속성

• 분석: 97%
• 광학 활성: [α]20/D +21°, c = 2 in chloroform
• refractive index: n20/D 1.501 (lit.)
• bp: 121 °C/0.1 mmHg (lit.)
• density: 0.94 g/mL at 25 °C (lit.)
• SMILES string: CCCCN(CCCC)[C@@H](C)[C@H](O)c1ccccc1
• InChI: 1S/C17H29NO/c1-4-6-13-18(14-7-5-2)15(3)17(19)16-11-9-8-10-12-16/h8-12,15,17,19H,4-7,13-14H2,1-3H3/t15-,17-/m0/s1
• InChI key: BRRGNOFUBFINSX-RDJZCZTQSA-N

설명

일반 설명

(1R,2S)-(+)-2-(Dibutylamino)-1-phenyl-1-propanol, a norephedrine derivative, is a chiral auxiliary for asymmetric synthesis.

애플리케이션

(+)-DBNE reacts with nickel bromide (NiBr₂) to form a chiral catalyst, which can catalyze the enantioselective conjugate addition of dialkylzincs to α,β-unsaturated ketones leading to the formation of optically active β-substituted ketones.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H315,H319,H335
• 예방조치 성명서: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point (°F): 230.0 °F - closed cup
• Flash Point (°C): 110 °C - closed cup
• 개인 보호 장비: Eyeshields, Gloves, type ABEK (EN14387) respirator filter