38827

4,4′-Dimethoxytriphenylmethyl chloride

≥97.0% (HPLC)

• 동의어(들): 4,4′-Dimethoxytrityl chloride, Chloro-4,4′-dimethoxytriphenylmethane, DMT, DMT-Cl
• 실험식(Hill 표기법): C₂₁H₁₉ClO₂
• CAS Number: 40615-36-9
• Molecular Weight: 338.83
• Beilstein: 2471942
• EC Number: 255-002-6
• MDL number: MFCD00008409
• UNSPSC 코드: 12352101
• PubChem Substance ID: 57649867
• NACRES: NA.22

속성

• 분석: ≥97.0% (HPLC)
• mp: 123-125 °C
• SMILES string: COc1ccc(cc1)C(Cl)(c2ccccc2)c3ccc(OC)cc3
• InChI: 1S/C21H19ClO2/c1-23-19-12-8-17(9-13-19)21(22,16-6-4-3-5-7-16)18-10-14-20(24-2)15-11-18/h3-15H,1-2H3
• InChI key: JBWYRBLDOOOJEU-UHFFFAOYSA-N
• 유전자 정보: human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358) ; rat ... Htr1a(24473) , Htr2a(29595)

설명

애플리케이션

4,4′-Dimethoxytriphenylmethyl chloride (DMTrCl) can be used as a protecting agent:

• For hydroxyl group of nucleosides/nucleotides as its O-(4,4′-dimethoxytrityl)derivative.
• For 1⁰ sulfhydryl group of oligonucleotide analogs as its DMTr thioether.

기타 정보

Useful protecting-group reagent; Removal

안전성 정보

• 픽토그램: GHS05,GHS07,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H314,H317,H335,H411
• 예방조치 성명서: P260 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• 표적 기관: Respiratory system
• Storage Class Code: 8B - Non-combustible corrosive hazardous materials
• WGK: WGK 3
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)