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Merck
모든 사진(1)

주요 문서

371858

Sigma-Aldrich

6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole hydrochloride

97%

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About This Item

실험식(Hill 표기법):
C12H14N2O · HCl
CAS Number:
Molecular Weight:
238.71
MDL number:
UNSPSC 코드:
12171500
PubChem Substance ID:

분석

97%

mp

288-290 °C (lit.)

SMILES string

Cl[H].COc1ccc2[nH]c3CNCCc3c2c1

InChI

1S/C12H14N2O.ClH/c1-15-8-2-3-11-10(6-8)9-4-5-13-7-12(9)14-11;/h2-3,6,13-14H,4-5,7H2,1H3;1H

InChI key

KRMJEIDSHZEQHJ-UHFFFAOYSA-N

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

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문서 라이브러리 방문

E Jane Cooper et al.
European journal of pharmacology, 482(1-3), 189-196 (2003-12-09)
It is well known that certain imidazoline compounds can stimulate insulin secretion and this has been attributed to the activation of imidazoline I(3) binding sites in the pancreatic beta-cell. Recently, it has been proposed that beta-carbolines may be endogenous ligands
R Pähkla et al.
Journal of pineal research, 24(2), 96-101 (1998-03-24)
Several recent experiments have shown that melatonin is an efficient antioxidant and free radical scavenger. In the present study the antioxidative effect of melatonin was compared with that of pinoline. Pinoline (6-methoxy-tetrahydro-beta-carboline) can be formed in the mammalian body under
R Pähkla et al.
Methods and findings in experimental and clinical pharmacology, 18(6), 359-366 (1996-07-01)
Pinoline (6-methoxy-1,2,3,4-tetrahydro-beta-carboline) has been found in similar concentrations to those of melatonin in various mammalian tissues. The present study investigates the subcellular distribution of in vivo administered [3H]-pinoline in mouse tissues using light and electron microscopic autoradiography. The antioxidative capacity
P T Männistö et al.
Medical biology, 65(5-6), 267-272 (1987-01-01)
Time relationships and mediators of the inhibitory effect of pinealectomy on cold-induced TSH secretion were studied in male Sprague-Dawley rats. Pinealectomy but not sham operation significantly reduced the TSH cold-response (30 min at +4 degrees C) in 6-8 week-old rats
Benny B Tam et al.
Clinical & experimental optometry, 87(3), 171-174 (2004-06-10)
Pinoline is a pineal indoleamine naturally found in the retina. This study compared the effects of pinoline and vitamin E on the copper (I)-induced retinal lipid peroxidation (LPO). Porcine retinal homogenates were mixed with 120 micro M copper (I) solution.

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