280550
4-Diphenylmethoxy-1-methylpiperidine hydrochloride
95%
동의어(들):
4-Diphenylmethoxy-1-methylpiperidine, Diphenylpyraline hydrochloride
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모든 사진(1)
About This Item
실험식(Hill 표기법):
C19H23NO · HCl
CAS Number:
Molecular Weight:
317.85
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22
추천 제품
분석
95%
mp
203-205 °C (lit.)
SMILES string
Cl[H].CN1CCC(CC1)OC(c2ccccc2)c3ccccc3
InChI
1S/C19H23NO.ClH/c1-20-14-12-18(13-15-20)21-19(16-8-4-2-5-9-16)17-10-6-3-7-11-17;/h2-11,18-19H,12-15H2,1H3;1H
InChI key
LPRLDRXGWKXRMQ-UHFFFAOYSA-N
유전자 정보
human ... HRH1(3269)
관련 카테고리
일반 설명
4-Diphenylmethoxy-1-methylpiperidine hydrochloride is also referred as diphenylpyraline hydrochloride (DPP), is a first-generation antihistamine.
애플리케이션
4-Diphenylmethoxy-1-methylpiperidine hydrochloride was used as a pharmacotherapy for Parkinson′s disease.
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
N Shibata et al.
Rinsho shinkeigaku = Clinical neurology, 30(9), 978-984 (1990-09-01)
Two sibling cases of cerebrotendinous xanthomatosis with parkinsonism were reported. One was a woman of 39 years old, and another was her sister of 36 years old. In both cases, febrile convulsion appeared on 1.5 year old, and mental deterioration
Gennady B Lapa et al.
European journal of pharmacology, 506(3), 237-240 (2005-01-04)
Diphenylpyraline hydrochloride (DPP) is used clinically as an antihistamine drug, but its neurobiological effects are not completely understood. Voltammetry and microdialysis were used to investigate potential actions of DPP on the dopamine system. Voltammetric monitoring of dopamine signals in mouse
K O Ebete et al.
Journal of chromatography. B, Biomedical applications, 677(2), 319-323 (1996-03-03)
A rapid, reliable and specific reversed-phase high-performance liquid chromatographic procedure is described for the determination of diphenylpyraline hydrochloride at nanogram concentrations in plasma and urine. After extraction of the drug with n-pentane-2-propanol (50:1) from alkalinized samples, the organic extract was
T Ohno et al.
Journal of the neurological sciences, 182(2), 95-97 (2001-01-04)
A long-term follow-up study was made of three patients with cerebrotendinous xanthomatosis (CTX) associated with parkinsonism, two of whom were siblings. Besides typical CTX symptoms, all three patients showed severe parkinsonism. This observation has been rarely reported in CTX. The
Chika Hasegawa et al.
Rapid communications in mass spectrometry : RCM, 20(4), 537-543 (2006-01-19)
Ten antihistamine drugs, diphenhydramine, orphenadrine, chlorpheniramine, diphenylpyraline, triprolidine, promethazine, homochlorcyclizine, cyproheptadine, cloperastine and clemastine, have been found to be extractable from human plasma samples using MonoTip C18 tips, inside which C18- bonded monolithic silica gel was fixed. Human plasma (0.1
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