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Merck
모든 사진(1)

주요 문서

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216267

Sigma-Aldrich

7,12-Dimethylbenz[a]anthracene

≥98%

동의어(들):

1,4-Dimethyl-2,3-benzophenanthrene, 9,10-Dimethyl-1,2-benzanthracene, DMBA

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모든 사진(1)

About This Item

실험식(Hill 표기법):
C20H16
CAS Number:
57-97-6
Molecular Weight:
256.34
Beilstein:
1912135
EC Number:
200-359-5
MDL number:
MFCD00003600
UNSPSC 코드:
12352103
PubChem Substance ID:
329752186

분석

≥98%

mp

122-123 °C (lit.)

SMILES string

Cc1c2ccccc2c(C)c3c1ccc4ccccc34

InChI

1S/C20H16/c1-13-16-8-5-6-9-17(16)14(2)20-18(13)12-11-15-7-3-4-10-19(15)20/h3-12H,1-2H3

InChI key

ARSRBNBHOADGJU-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

One of the most potent carcinogenic polycyclic aromatic hydrocarbons.

교체됨

제품 번호
설명
가격

픽토그램

Health hazardExclamation mark
GHS08,GHS07

신호어

Danger

유해 및 위험 성명서

H302,H350

예방조치 성명서

P201 - P308 + P313

Hazard Classifications

Acute Tox. 4 Oral - Carc. 1B

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

가장 최신 버전 중 하나를 선택하세요:

시험 성적서(COA)

Lot/Batch Number
10403AI
07019EW
06561CN
06221JS
05920EZ

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특정 버전이 필요한 경우 로트 번호나 배치 번호로 특정 인증서를 찾을 수 있습니다.

COA 검색

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

A Garg et al.
International journal of oncology, 3(2), 185-189 (1993-08-01)
The ability of the mammary procarcinogen 7,12-dimethylbenz(a)anthracene (DMBA) to induce the expression of selected molecular and cellular biomarkers for preneoplastic transformation is examined in a newly developed, immortalized but nontumorigenic mammary epithelial cell line C57/MG. This cell line is established
J DiGiovanni et al.
Drug metabolism reviews, 11(1), 61-101 (1980-01-01)
As the result of rapidly developing technological advances, our understanding of the biotransformation and bioactivation of 7, 12-DMBA has increased markedly in recent years. In terms of the metabolic conversion of this polynuclear aromatic hydrocarbon to reactive mutagen/carcinogens, the "bay
Ramar Perumal Samy et al.
PloS one, 7(12), e48514-e48514 (2013-01-04)
Breast cancer is the most common cancer among women. To date, improvements in hormonal and cytotoxic therapies have not yet led to a sustained remission or cure. In the present study, we investigated the in vitro and in vivo antitumor
Anthony J Apostoli et al.
International journal of cancer, 134(5), 1055-1066 (2013-08-13)
Breast cancer is the leading cause of new cancer diagnoses among women. Using peroxisome proliferator-activated receptor (PPAR)γ((+/-)) mice, we showed normal expression of PPARγ was critical to stop 7,12-dimethylbenz[a]anthracene (DMBA)-induced breast tumorigenesis. PPARγ is expressed in many breast cell types
E Hallberg
Journal of biochemical toxicology, 5(2), 71-90 (1990-01-01)
The adrenal cortex contains high amounts of detoxifying enzymes, as well as generators and protectors of reactive oxygen species. The high content of cytochrome P-450 enzymes in the adrenal cortex together with its remarkable tendency to accumulate hydrophobic substances probably
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