162906
2-Hydroxy-5-nitrobenzyl bromide
90%
동의어(들):
α-Bromo-4-nitro-o-cresol, 2-Bromomethyl-4-nitrophenol, Koshland I, Koshland’s Reagent I
로그인조직 및 계약 가격 보기
모든 사진(2)
About This Item
Linear Formula:
HOC6H3(NO2)CH2Br
CAS Number:
Molecular Weight:
232.03
Beilstein:
1868798
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22
추천 제품
분석
90%
형태
solid
mp
144-149 °C (lit.)
solubility
chloroform: soluble 25 mg/mL, clear, yellow
저장 온도
2-8°C
SMILES string
Oc1ccc(cc1CBr)[N+]([O-])=O
InChI
1S/C7H6BrNO3/c8-4-5-3-6(9(11)12)1-2-7(5)10/h1-3,10H,4H2
InChI key
KFDPCYZHENQOBV-UHFFFAOYSA-N
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일반 설명
2-Hydroxy-5-nitrobenzyl bromide is a protein modifying reagent.
애플리케이션
2-Hydroxy-5-nitrobenzyl bromide was used in covalent modification of tryptophan and tryptophan residues in monoclonal immunoglobulin. It was also used as reagent for sulfhydryl modification
기타 정보
Contains 2-hydroxy-5-nitrobenzyl alcohol
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
A Baracca et al.
Biochemistry international, 21(6), 1135-1142 (1990-09-01)
The incubation of bovine mitochondrial F1-ATPase with 2-hydroxy-5-nitrobenzyl bromide (HNB), a selective reagent toward tryptophan residues in proteins, produced a concentration dependent inactivation of the enzyme and the covalent binding of 0.88 mol reagent/mol F1. Although HNB is highly specific
S S Keskar et al.
The Biochemical journal, 261(1), 49-55 (1989-07-01)
Extracellular xylanase produced in submerged culture by a thermotolerant Streptomyces T7 growing at 37-50 degrees C was purified to homogeneity by chromatography on DEAE-cellulose and gel filtration on Sephadex G-50. The purified enzyme has an Mr of 20,463 and a
V A Lapuk et al.
Biokhimiia (Moscow, Russia), 50(2), 237-242 (1985-02-01)
The modification of tryptophan residues in monoclonal immunoglobulin M (IgM) by 2-hydroxy-5-nitrobenzyl bromide (RK) was studied at pH 2.0-2.85 and 7.0 and a RK to tryptophan molar ratio (K) from 1 to 40. At pH 2.85, the number of RK
G Solaini et al.
The Biochemical journal, 327 ( Pt 2), 443-448 (1997-11-14)
Treatment of bovine heart submitochondrial particles with a low concentration of 2-hydroxy-5-nitrobenzyl bromide (HNB), a selective reagent for the Trp residue of the epsilon subunit [Baracca, Barogi, Lenaz and Solaini (1993) Int. J. Biochem. 25, 1269-1275], enhances the ATP hydrolytic
A I Korneliuk et al.
Bioorganicheskaia khimiia, 11(5), 605-612 (1985-05-01)
The structural accessibility of tryptophan residues in leucyl-tRNA synthetase from cow mammary gland has been studied using chemical modifications by N-bromosuccinimide and 2-hydroxy-5-nitrobenzyl bromide. The modifications were monitored by UV absorbance and intrinsic fluorescence of the enzyme's tryptophan residues. Under
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