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Merck
모든 사진(2)

문서

158194

Sigma-Aldrich

2,2′-Dithiobis(5-nitropyridine)

96%

동의어(들):

Bis(5-nitro-2-pyridyl) disulfide, DTNP

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About This Item

실험식(Hill 표기법):
C10H6N4O4S2
CAS Number:
Molecular Weight:
310.31
Beilstein:
305413
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22

분석

96%

형태

solid

mp

155-157 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(SSc2ccc(cn2)[N+]([O-])=O)nc1

InChI

1S/C10H6N4O4S2/c15-13(16)7-1-3-9(11-5-7)19-20-10-4-2-8(6-12-10)14(17)18/h1-6H

InChI key

ROUFCTKIILEETD-UHFFFAOYSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

2,2′-Dithiobis(5-nitropyridine) is an aromatic disulphide.

애플리케이션

2,2′-Dithiobis(5-nitropyridine) was employed:
  • as cysteine-activating reagent to study the NMR of G protein-coupled receptors
  • in the deprotection assays for protected selenocysteine-containing peptides
  • for deprotecting p-methoxybenzyl groups and acetamidomethyl groups from the side-chains of cysteine and selenocysteine
  • to remove the p-methoxybenzyl protecting group from cysteine and selenocysteine side-chains

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Katharine M Harris et al.
Journal of peptide science : an official publication of the European Peptide Society, 13(2), 81-93 (2006-10-13)
We present here a simple method for deprotecting p-methoxybenzyl groups and acetamidomethyl groups from the side-chains of cysteine and selenocysteine. This method uses the highly elecrophilic, aromatic disulfides 2,2'-dithiobis(5-nitropyridine) (DTNP) and 2,2'-dithiodipyridine (DTP) dissolved in TFA to effect removal of
Uncoupling and energy transfer inhibition of photophosphorylation by sulfhydryl reagents.
J V Moroney et al.
The Journal of biological chemistry, 255(14), 6670-6674 (1980-07-25)
Chi-Pan Hsieh
Biochemical and biophysical research communications, 370(3), 445-449 (2008-04-01)
Redox modulation of fast inactivation has been described in certain cloned A-type voltage-gated K(+) (Kv) channels in expressing systems, but the effects remain to be demonstrated in native neurons. In this study, we examined the effects of cysteine-specific redox agents
K Yamaoka et al.
Pflugers Archiv : European journal of physiology, 440(2), 207-215 (2000-07-18)
The effects of sulfhydryl (SH) reagents on the L-type Ca current (ICa) were studied in frog ventricular myocytes using the whole-cell patch-clamp method. Methanethiosulfonate ethylammonium (MTSEA+) was found to enter the cell through the membrane and cause a remarkable increase
Effects of oxidants on membrane potential, K+ and Ca2+ currents of mouse pancreatic B-cells.
P Krippeit-Drews et al.
Advances in experimental medicine and biology, 426, 355-359 (1997-01-01)

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