133655

4′-Chloroacetoacetanilide

98%

• Linear Formula: CH₃COCH₂CONHC₆H₄Cl
• CAS Number: 101-92-8
• Molecular Weight: 211.64
• EC Number: 202-989-6
• MDL number: MFCD00000613
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24848116
• NACRES: NA.22

속성

• 분석: 98%
• 양식: powder
• mp: 131-134 °C (lit.)
• solubility: acetone: soluble 25 mg/mL, clear, colorless to light yellow
• SMILES string: CC(=O)CC(=O)Nc1ccc(Cl)cc1
• InChI: 1S/C10H10ClNO2/c1-7(13)6-10(14)12-9-4-2-8(11)3-5-9/h2-5H,6H2,1H3,(H,12,14)
• InChI key: JMRJWEJJUKUBEA-UHFFFAOYSA-N

설명

일반 설명

4′-Chloroacetoacetanilide was trilithiated with lithium diisopropylamide and condensed with several aromatic esters, followed by neutralization, separate acid cyclization and rearrangements to yield 4-anilino-6-aryl-2H-pyran-2-ones. It undergoes three-component reaction with a mixture of aromatic aldehyde and 5-aminotetrazole to form N,7-diaryl-5-methyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxamide.

애플리케이션

4′-Chloroacetoacetanilide was used in recombinant androgen receptor competitive binding assay for analysis of natural, synthetic and environmental chemicals.

안전성 정보

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)