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Merck
모든 사진(1)

주요 문서

131628

Sigma-Aldrich

4-Pyridinealdoxime

98%

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About This Item

실험식(Hill 표기법):
C6H6N2O
CAS Number:
Molecular Weight:
122.12
Beilstein:
2079
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:

분석

98%

mp

130-133 °C (lit.)

SMILES string

[H]\C(=N\O)c1ccncc1

InChI

1S/C6H6N2O/c9-8-5-6-1-3-7-4-2-6/h1-5,9H/b8-5+

InChI key

OFYLBLSSPQTTHT-VMPITWQZSA-N

애플리케이션

4-Pyridinealdoxime was used in the chromatographic separation and NMR characterization of the isomers of 1,1′-Methylenebis{4-[(hydroxyimino)methyl]pyridinium) dichloride.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


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시험 성적서(COA)

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문서 라이브러리 방문

G R Veera Babu et al.
Archives internationales de physiologie et de biochimie, 97(2), 205-209 (1989-04-01)
Effects in vitro of benthiocarb on rat brain Mg2+-ATPase were studied to elucidate the interaction of benthiocarb with Mg2+-ATPase. Based on IC50 values, it was evident that Mg2+-ATPase was sensitive to benthiocarb. Non-competitive inhibition with respect to activation by ATP
Tsung-Ming Shih et al.
Archives of toxicology, 83(12), 1083-1089 (2009-09-19)
Methoxime (MMB-4) is a leading candidate oxime acetylcholinesterase (AChE) reactivator to replace pralidoxime (2-PAM) for therapeutic treatment of nerve agent intoxication. 4-Pyridine aldoxime (4-PA) is a synthetic starting material, a breakdown product, and a probable metabolite of MMB-4. There is
[Capillary isotachophoresis--a new method in drug analysis. 4. Analytic capillary tachophoresis of obidoxime and pyridine-4-aldoxime].
R Jannasch
Die Pharmazie, 41(7), 511-512 (1986-07-01)
Patrick Macauley et al.
Journal of pharmaceutical and biomedical analysis, 49(4), 889-894 (2009-02-17)
1,1'-Methylenebis{4-[(hydroxyimino)methyl]pyridinium) dichloride (MMB-4), a promising antidote for organophosphate poisoning, has been shown by chromatography and NMR to be a mixture of geometric isomers, predominantly the E/E form. The chromatographically separated isomers have been isolated, directly characterized by NMR to be
Aditya Kapil Valiveti et al.
Chemico-biological interactions, 237, 125-132 (2015-06-14)
A series of mono pyridinium oximes linked with arenylacetamides as side chains were synthesized and their in vitro reactivation potential was evaluated against human acetylcholinesterase (hAChE) inhibited by organophosphorus inhibitors (OP) such as sarin, VX and tabun. The reactivation data

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