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Merck

WT1

Wilms tumor 1

동의어:
AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33
:
UniProtKB ID:
Clone ID:
  • Human(7490) Summary: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]
  • Mouse(22431) Wilms tumor 1 homolog
  • Rat(24883) Wilms tumor 1
  • domestic guinea pig(100716139) Wilms tumor 1
  • dog(609253) Wilms tumor 1
  • sheep(100101227) Wilms tumor 1
  • naked mole-rat(101714640) Wilms tumor 1
  • cow(280959) Wilms tumor 1
  • chicken(396139) Wilms tumor 1
  • cow(782183) Wilms tumor 1
  • cow(614584) Wilms tumor 1
  • domestic cat(101088518) Wilms tumor 1

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-WT1 Antibody, clone 6F-H2, clone 6F-H2, Upstate®, from mouse,
종별 반응성
human
응용분야
immunocytochemistry
immunohistochemistry

western blot
Anti-Wilms Tumor Protein Antibody, clone 2O18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
종별 반응성
human, monkey, mouse, rat
응용분야
immunocytochemistry
immunohistochemistry

western blot
Anti-WT1, affinity isolated antibody,
종별 반응성
dog, human, mouse, rabbit, rat
응용분야
immunohistochemistry
western blot
Anti-WT1 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
western blot
Anti-WT1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13170, purified by using Protein A, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot

Proteins

제품 번호
설명
WT-1 (+KTS) human, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
human
WT-1 (-KTS) human, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human WT1,
human