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Merck

TEK

TEK tyrosine kinase, endothelial

동의어:
CD202B, TIE-2, TIE2, VMCM, VMCM1
:
UniProtKB ID:
Clone ID:
  • Human(7010) Summary: The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase. [provided by RefSeq, Jul 2008]
  • Mouse(21687) endothelial-specific receptor tyrosine kinase
  • Rat(89804) TEK tyrosine kinase, endothelial
  • chicken(427368) TEK tyrosine kinase, endothelial
  • Zebrafish(30747) TEK tyrosine kinase, endothelial
  • dog(403714) TEK tyrosine kinase, endothelial
  • domestic cat(101091977) TEK tyrosine kinase, endothelial
  • cow(280939) TEK tyrosine kinase, endothelial
  • domestic guinea pig(100713324) TEK tyrosine kinase, endothelial
  • naked mole-rat(101710501) TEK tyrosine kinase, endothelial

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ELISA

제품 번호
설명
Rat Tie-2 ELISA, for serum, plasma and cell culture supernatants,
rat
Phosphotyrosine TEK / Angiopoietin-1 Receptor ELISA Kit, ,
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-Phospho-TEK-pY1113 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
dot blot
Monoclonal Anti-TEK antibody produced in mouse, clone 1A4, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-TIE2, C-Terminal antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human, mouse
응용분야
ELISA
immunohistochemistry
Monoclonal Anti-TEK antibody produced in mouse, clone 3F8, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti-Phospho-TEK-Y992 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
dot blot

Small Molecule - Inhibitor

제품 번호
설명
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
human

Proteins

제품 번호
설명
TIE2 (771-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Tek,
mouse
MISSION® esiRNA, targeting human TEK,
human