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Merck

SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

동의어:
BAF190, BAF190A, BRG1, MRD16, RTPS2, SNF2, SNF2L4, SNF2LB, SWI2, hSNF2b
:
UniProtKB ID:
Clone ID:
  • Human(6597) Summary: The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
  • Mouse(20586) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • Rat(171379) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • dog(476710) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • sheep(101116565) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • domestic cat(101097046) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • Zebrafish(353295) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • chicken(395932) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • cow(414274) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • naked mole-rat(101700987) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  • domestic guinea pig(100719729) SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-Smarca4 Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13783, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunohistochemistry
Monoclonal Anti-Smarca4 Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL13779, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti- BRG1/SMARCA4 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
immunohistochemistry
western blot
Anti-SMARCA4 antibody produced in rabbit, ,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry

western blot
Anti-BRG1/SMARCA4 antibody produced in rabbit, ,
종별 반응성
human, mouse, rat
응용분야
western blot

Proteins

제품 번호
설명
BRG1, wild type human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
human
BRG1 (1480-1603) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human SMARCA4,
human