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Merck

SLC6A4

solute carrier family 6 (neurotransmitter transporter), member 4

동의어:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
:
UniProtKB ID:
Clone ID:
  • Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
  • Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
  • domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

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Small Molecule - Antagonist

제품 번호
설명
Diphenyl-4-pyridylmethane, 99%,
rat
N-Ethylmaleimide, purum p.a., ≥99.0% (HPLC),
human
N-Ethylmaleimide, BioUltra, ≥99.0% (HPLC),
human
4-Benzylpyridine, 98%,
rat
N-Ethylmaleimide, BioXtra, ≥98% (HPLC),
human

Antibodies

제품 번호
설명
종별 반응성
응용분야
Monoclonal Anti-SLC6A4 antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
Anti-Serotonin (5-HT) Transporter (602-622) Rabbit pAb, lyophilized, Calbiochem®,
종별 반응성
mouse, rat
응용분야
Anti-SLC6A4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
종별 반응성
human
응용분야
immunofluorescence
Anti-SLC6A4 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
bovine, human, mouse, rat
응용분야
ELISA
flow cytometry

immunofluorescence
Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
종별 반응성
human
응용분야
western blot

Small Molecule - Inhibitor

제품 번호
설명
Paroxetine hydrochloride hemihydrate, ≥98% (HPLC), powder,
human
Paroxetine hydrochloride hemihydrate, European Pharmacopoeia (EP) Reference Standard,
human
Escitalopram oxalate, ≥98% (HPLC), powder,
human
Dapoxetine hydrochloride, ≥98% (HPLC),
human
Sertraline hydrochloride, United States Pharmacopeia (USP) Reference Standard,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting human SLC6A4,
human