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Merck

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

동의어:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
:
UniProtKB ID:
Clone ID:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-COX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
종별 반응성
human
응용분야
immunofluorescence
immunohistochemistry
Anti-COX2 antibody produced in rabbit, affinity isolated antibody,
종별 반응성
human
응용분야
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-COX2/PTGS2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
종별 반응성
bovine, canine, human, pig, sheep
응용분야
ELISA
flow cytometry

immunofluorescence

western blot
Anti-COX2 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP21, tissue culture supernatant,
종별 반응성
bovine, dog, frog, human, mouse, rat
응용분야
immunohistochemistry
Anti-COX-2 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM348, purified immunoglobulin,
종별 반응성
human
응용분야
immunohistochemistry

Small Molecule - Blocker

제품 번호
설명
N-p-Tosyl-L-phenylalanine chloromethyl ketone, ≥97% (TLC), powder,
human

Small Molecule - Inhibitor

제품 번호
설명
Valdecoxib, ≥98% (HPLC),
human
Celecoxib, European Pharmacopoeia (EP) Reference Standard,
human
Celecoxib, United States Pharmacopeia (USP) Reference Standard,
human
Celecoxib, Pharmaceutical Secondary Standard; Certified Reference Material,
human
Carprofen for system suitability, European Pharmacopoeia (EP) Reference Standard,
human

Proteins

제품 번호
설명
Cyclooxygenase 2 human, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
human

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Ptgs2,
mouse
MISSION® esiRNA, targeting human PTGS2,
human